AUTHOR=Davidson Benjamin , Lipsman Nir , Meng Ying , Rabin Jennifer S. , Giacobbe Peter , Hamani Clement 

TITLE=The Use of Tractography-Based Targeting in Deep Brain Stimulation for Psychiatric Indications

JOURNAL=Frontiers in Human Neuroscience

VOLUME=14

YEAR=2020

URL=https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2020.588423

DOI=10.3389/fnhum.2020.588423

ISSN=1662-5161

ABSTRACT=<p>Deep Brain Stimulation (DBS) has been investigated as a treatment option for patients with refractory psychiatric illness. Over the past two decades, neuroimaging developments have helped to advance the field, particularly the use of diffusion tensor imaging (DTI) and tractographic reconstruction of white-matter pathways. In this article, we review translational considerations and how DTI and tractography have been used to improve targeting during DBS surgery for depression, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD).</p>