AUTHOR=Bashir Shahid , Al-Hussain Fawaz , Hamza Ali , Shareefi Ghadah Faisal , Abualait Turki , Yoo Woo-Kyoung 

TITLE=Role of Single Low Pulse Intensity of Transcranial Magnetic Stimulation Over the Frontal Cortex for Cognitive Function

JOURNAL=Frontiers in Human Neuroscience

VOLUME=14

YEAR=2020

URL=https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2020.00205

DOI=10.3389/fnhum.2020.00205

ISSN=1662-5161

ABSTRACT=<p><bold>Background</bold>: The principal aim of this study was to measure the effect of online single-pulse transcranial magnetic stimulation (TMS) over the right dorsolateral prefrontal cortex (DLPFC) on cognition <italic>via</italic> the Cambridge Neuropsychological Test Automated Battery (CANTAB) in healthy individuals.</p><p><bold>Methods</bold>: In a single-blind, sham-controlled study, we assessed both 50% and 60% of the resting motor threshold (RMT) over the right DLPFC in healthy right-handed (<italic>n</italic> = 42) adults using cognitive function, such as attention and memory, as a measure <italic>via</italic> CANTAB.</p><p><bold>Results</bold>: We observed an improvement in the cognitive function level during the use of online low intensities of 50% and 60% RMT active stimulation of the DLPFC compared to the sham stimulation.</p><p><bold>Conclusions</bold>: The results showed that low-intensity TMS can indeed effectively modulate cognitive function in DLPFC. Future research is, however, necessary to investigate the potential effects of low-intensity TMS on different brain areas to increase confidence in the observed results.</p>