The Impact of Aerobic Exercise on Fronto-Parietal Network Connectivity and Its Relation to Mobility: An Exploratory Analysis of a 6-Month Randomized Controlled Trial
- 1Aging, Mobility, and Cognitive Neuroscience Lab, University of British Columbia, Vancouver, BC, Canada
- 2Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada
- 3Djavad Mowafaghian Center for Brain Health, University of British Columbia, Vancouver, BC, Canada
- 4Center for Hip Health and Mobility, Vancouver, BC, Canada
- 5Health, Brain and Cognition Lab, University of Iowa, Iowa City, IA, United States
- 6Department of Psychology, University of Iowa, Iowa City, IA, United States
- 7Department of Medicine, University of British Columbia, Vancouver, BC, Canada
- 8Department of Psychology, University of British Columbia, Vancouver, BC, Canada
by Hsu, C. L., Best, J. R., Wang, S., Voss, M. W., Hsiung, R. G. Y., Munkacsy, M., et al. (2017). Front. Hum. Neurosci. 11:344. doi: 10.3389/fnhum.2017.00344
In the original article, we used inconsistent wording that, while not incorrect, may cause confusion for readers. In the discussion section and the conclusion, we indicated that we found aerobic training may alter functional network connectivity. For greater clarity, we should have stated that aerobic training maintains network connectivity.
The following corrections, in italics, have been made to Discussion, Paragraph 1.
Contrary to our initial hypothesis, we found that a 6-month AT intervention did not significantly increase, but rather maintained FPN connectivity during right finger tapping among older adults with mild SIVCI. The observed effect of aerobic exercise on the FPN during right tapping was significantly associated with improved mobility and cardiovascular capacity. While these results are preliminary, our data suggest aerobic exercise may promote mobility among older adults with mild SIVCI by maintaining the integrity of FPN connectivity.
Also, a correction has been made to Conclusion, Paragraph 1.
Our results demonstrate that neural network functional connectivity may contribute to the effects of aerobic exercise on mobility among older adults with SIVCI. We observed that 6 months of AT maintained motor task-based connectivity within the FPN of older adults with SIVCI, and the degree of decoupling within this region correlated with improvements in mobility. As such, our current findings support emerging results from others that lower functional connectivity within certain neural networks might represent a beneficial change in older adults with mild SIVCI, especially vis-à-vis their mobility. More broadly, these results bring further support to the burgeoning notion that functional neural changes contribute to exercised-induced improvements to mobility among older adults. As an extension of these findings, future studies should explore potential interactions between mobility and cognitive outcomes among this population.
The authors apologize for this issue and state that this does not change the scientific conclusions of the article in any way.
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Keywords: aging, impaired mobility, vascular cognitive impairment, fronto-parietal network, functional connectivity, fMRI
Citation: Hsu CL, Best JR, Wang S, Voss MW, Hsiung RGY, Munkacsy M, Cheung W, Handy TC and Liu-Ambrose T (2017) Corrigendum: The Impact of Aerobic Exercise on Fronto-Parietal Network Connectivity and Its Relation to Mobility: An Exploratory Analysis of a 6-Month Randomized Controlled Trial. Front. Hum. Neurosci. 11:449. doi: 10.3389/fnhum.2017.00449
Received: 02 August 2017; Accepted: 23 August 2017;
Published: 05 September 2017.
Edited and reviewed by: Srikantan S. Nagarajan, University of California, San Francisco, United States
Copyright © 2017 Hsu, Best, Wang, Voss, Hsiung, Munkacsy, Cheung, Handy and Liu-Ambrose. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Teresa Liu-Ambrose, dGVyZXNhLmFtYnJvc2VAdWJjLmNh