AUTHOR=Meneses Francisco M. , Queirós Fernanda C. , Montoya Pedro , Miranda José G. V. , Dubois-Mendes Selena M. , Sá Katia N. , Luz-Santos Cleber , Baptista Abrahão F. TITLE=Patients with Rheumatoid Arthritis and Chronic Pain Display Enhanced Alpha Power Density at Rest JOURNAL=Frontiers in Human Neuroscience VOLUME=10 YEAR=2016 URL=https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2016.00395 DOI=10.3389/fnhum.2016.00395 ISSN=1662-5161 ABSTRACT=
Patients with chronic pain due to neuropathy or musculoskeletal injury frequently exhibit reduced alpha and increased theta power densities. However, little is known about electrical brain activity and chronic pain in patients with rheumatoid arthritis (RA). For this purpose, we evaluated power densities of spontaneous electroencephalogram (EEG) band frequencies (delta, theta, alpha, and beta) in females with persistent pain due to RA. This was a cross-sectional study of 21 participants with RA and 21 healthy controls (mean age = 47.20; SD = 10.40). EEG was recorded at rest over 5 min with participant's eyes closed. Twenty electrodes were placed over five brain regions (frontal, central, parietal, temporal, and occipital). Significant differences were observed in depression and anxiety with higher scores in RA participants than healthy controls (