Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at Referral Hospitals of Amhara Regional State, institutional-based cross-sectional study

Melesse, Misganaw Fikriee; Lake, Getie; Badi, Martha Berta; Aynalem, Bewket Yeserah

doi:10.3389/fgwh.2025.1555778

ORIGINAL RESEARCH article

Front. Glob. Womens Health

Sec. Maternal Health

Volume 6 - 2025 | doi: 10.3389/fgwh.2025.1555778

Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at Referral Hospitals of Amhara Regional State, institutional-based cross-sectional study

Provisionally accepted

Misganaw Fikriee Melesse ¹

Getie Lake ²

Martha Berta Badi ³

Bewket Yeserah Aynalem ^1*

¹ Department of Midwifery, College of Health Science, Debre Markos University, Debre Markos, Amhara, Ethiopia
² Department of Clinical Midwifery, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Amhara Region, Ethiopia
³ Department of General Midwifery, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Amhara Region, Ethiopia

The final, formatted version of the article will be published soon.

Severe preeclampsia/eclampsia is a multi-systemic pregnancy condition that manifests after 20 weeks of gestation and is linked to a high global rate of maternal morbidity and mortality. It is responsible for 11-14% of maternal mortality globally and is the second most frequent direct obstetrical cause of death. This study aimed to assess maternal outcomes of severe preeclampsia/eclampsia and associated factors in mothers admitted to referral hospitals in the Amhara Regional State of North West Ethiopia.An institutionally based cross-sectional investigation on the outcomes of severe preeclampsia/eclampsia in mothers was carried out from April 1 to September 30, 2018Using the census sampling technique, 456 study participants were included in the study. Data were coded, verified, and imported into Epi-info version 7.2 before being exported and analyzed in SPSS version 26. To determine the determinants of maternal outcomes of severe preeclampsia or eclampsia, binary logistic regression was employed, with a significance level of 95% confidence interval of odds ratio at p-value 0.05 or below.Overall, severe preeclampsia and eclampsia were shown to have unfavorable maternal outcomes in 37.7% (95% CI: 32.8%, 42.3%). The following variables had statistically significant associations with unfavorable maternal outcomes of severe preeclampsia and eclampsia:

Keywords: Preeclampsia, Eclampsia, maternal outcomes, pregnant women's health, Ethiopia

Received: 05 Jan 2025; Accepted: 17 Mar 2025.

Copyright: © 2025 Melesse, Lake, Badi and Aynalem. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Bewket Yeserah Aynalem, Department of Midwifery, College of Health Science, Debre Markos University, Debre Markos, Amhara, Ethiopia

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