Epidemiology of second trimester induced abortion in Ethiopia: A Systematic Review and Meta-Analysis

Mesfin Abebe^1*Nebiha Yimer¹Tsion Mulat Tebeje²Tesfaye Temesgen¹Getnet Melaku¹Habtamu Endashaw Hareru²

• ¹Department of Midwifery, College of Health and Medical Science, Dilla University, Dilla, Ethiopia
• ²School of Public Health, College of Health and Medical Science, Dilla University, Dilla, SNNPR, Ethiopia

Background: Second trimester induced abortion refers to the termination of a pregnancy occurring between 13 and 28 weeks of gestation in Africa. These abortions are particularly concerning due to the heightened risk of complications and maternal mortality. In Ethiopia, there is a lack of nationally representative data regarding the magnitude and associated factors of second trimester induced abortions. This systematic review and meta-analysis aimed to ascertain the pooled magnitude and identify the factors associated with second trimester induced abortions in Ethiopia. The PRISMA guidelines were used to review and report this research. A systematic literature search was conducted to identify relevant articles from online databases, including PubMed/MEDLINE, Web of Science, Google Scholar, and Ethiopian University online repositories. Data were extracted using an Excel data extraction format, and analysis was performed using Stata version 17. A meta-analysis was conducted using a random-effects model, and subgroup analysis was performed. In this review, a total of ten articles encompassing 4,466 participants were analyzed. The pooled prevalence of second trimester induced abortion in Ethiopia was found to be 29.10% (95% CI: 19.96 -38.24; I² = 97.84, P < 0.000). Delay in confirming pregnancy (POR = 4.33, 95% CI: 2.25, 8.32), nature of the menstrual cycle (POR = 0.32, 95% CI: 0.18, 0.56), residence (POR = 0.38, 95% CI: 0.30, 0.49), and pregnancy intention (POR = 0.28, 95% CI: 0.28, 0.42) were significantly associated with second trimester induced abortion. The magnitude of induced second-trimester abortions in Ethiopia is significantly higher than global data. This meta-analysis identifies several factors associated with second trimester abortions, including delayed pregnancy confirmation, irregular menstrual cycles, rural residency, and unplanned pregnancies. The findings highlight the urgent need for targeted interventions to address these factors and decrease the incidence of second-trimester abortions. Encouraging early pregnancy testing and confirmation to reduce delays, raising awareness about the importance of regular menstrual cycles and seeking medical advice for irregularities, improving healthcare services in rural areas to reduce disparities, and strengthening family planning and counseling services can help mitigate unplanned pregnancies and induced abortions.