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ORIGINAL RESEARCH article

Front. Glob. Womens Health
Sec. Infectious Diseases in Women
Volume 5 - 2024 | doi: 10.3389/fgwh.2024.1453231

Determinants of hepatitis B virus infection among pregnant women in Bench Sheko zone, southwest Ethiopia: A case-control study

Provisionally accepted
Tewodros Yosef Tewodros Yosef *Ephrem Eyasu Ephrem Eyasu Nigusie Shifera Nigusie Shifera Gossa F. Abebe Gossa F. Abebe Desalegn Girma Desalegn Girma Aklilu H. Hailegebireal Aklilu H. Hailegebireal Ahmed Fentaw Ahmed Fentaw Adane Asefa Adane Asefa
  • Mizan Tepi University, Mīzan Teferī, Ethiopia

The final, formatted version of the article will be published soon.

    Background: Hepatitis B Virus (HBV) infection during pregnancy poses serious risks by raising the likelihood of chronic infection in newborns by 90% and the risk of cirrhosis and liver cancer by 25% in chronic infections. This study aimed to identify determinants of HBV infection among pregnant women in the Bench Sheko zone, Southwest Ethiopia.Methods: An unmatched case-control study was conducted from May 15 to July 15, 2022, in selected health facilities of the Bench Sheko zone, Southwest Ethiopia. Medical charts were reviewed to collect the HBsAg status of participants, as all pregnant women attending antenatal care underwent routine screening. It involved 228 pregnant women (76 HBV-positive cases and 152 HBV-negative controls). Data were collected using structured questionnaires, and analyzed using SPSS 21. A multivariable logistic regression was performed to identify significant determinants of HBV infection, and statistical significance was declared at p-value < 0.05.Results: After controlling potential confounders, having no formal education (AOR = 4.94,

    Keywords: Hepatitis B virus, viral infection, Pregnant Women, Sero-prevalence, Southwest Ethiopia

    Received: 22 Jun 2024; Accepted: 30 Sep 2024.

    Copyright: © 2024 Yosef, Eyasu, Shifera, Abebe, Girma, Hailegebireal, Fentaw and Asefa. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Tewodros Yosef, Mizan Tepi University, Mīzan Teferī, Ethiopia

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