AUTHOR=Milton Rebecca , Zara Modibbo Fatima , Watkins William John , Gillespie David , Alkali Fatima Ibrahim , Bello Murjanatu , Edwin Chinagozi Precious , Habib Sa ad Fatima , Hood Kerenza , Iregbu Kenneth , Kassim Aishatu , Khalid Rashida Yakubu , Muhammad Maryam Yahaya , Mukaddas Aisha Sani , Ogudo Ese , Tukur Fatima Muhammad , Walsh Timothy Rutland TITLE=Determinants of Stillbirth From Two Observational Studies Investigating Deliveries in Kano, Nigeria JOURNAL=Frontiers in Global Women's Health VOLUME=2 YEAR=2022 URL=https://www.frontiersin.org/journals/global-womens-health/articles/10.3389/fgwh.2021.788157 DOI=10.3389/fgwh.2021.788157 ISSN=2673-5059 ABSTRACT=Background:

Stillbirths are a poignant representation of global inequality. Nigeria is documented to have the second highest rate; yet, the reporting system is inadequate in most Nigerian healthcare facilities. The aim was to identify the determinants of stillbirth among deliveries in the Murtala Muhammad Specialist Hospital (MMSH), Kano, Nigeria.

Methods:

Two study designs were used: a case-control study (S1) and a prospective cohort study (S2). Both studies were carried out at the MMSH. For S1, stillbirths were retrospectively matched to a livebirth by time (target of 24 hours' time variation) to establish a case-control study with a 1:1 ratio. Eligibility into S2 included all mothers who were presented at the MMSH in labour regardless of birth outcome. Both were based on recruitment durations, not sample sizes (3 months and 2 months, respectively, 2017–2018). The demographic and clinical data were collected through paper-based questionnaires. Univariable logistic regression was used. Multivariable logistic regression was used to explore relationships between area type and other specific factors.

Findings:

Stillbirth incidence in S2 was 180/1,000 births. Stillbirth was associated with the following factors; no maternal education, previous stillbirth(s), prematurity, living in both semi-rural and rural settings, and having extended time periods between rupture of membranes and delivery. Findings of the multivariable analysis (S1 and S2) indicated that the odds of stillbirth, for those living in a rural area, were further exacerbated in those mothers who had no education, lived in a shack, or had any maternal disease.

Interpretation:

This research identifies the gravity of this situation in this area and highlights the need for action. Further understanding of some of the findings and exploration into associations are required to inform intervention development.

Funding:

This collaboration was partially supported by funding from Health and Care Research Wales.