Review

Published on 22 Feb 2023

In search of an ideal template for therapeutic genome editing: A review of current developments for structure optimization

in Genome Editing in Blood Disorders

Alena Shakirova
Timofey Karpov
Yaroslava Komarova
Kirill Lepik

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1068637

6,474 views
6 citations

Original Research

Published on 20 Feb 2023

T-CAST: An optimized CAST-Seq pipeline for TALEN confirms superior safety and efficacy of obligate-heterodimeric scaffolds

in Genome Editing Tools and Mechanisms

Manuel Rhiel
Kerstin Geiger
Geoffroy Andrieux
Julia Rositzka
Melanie Boerries
Toni Cathomen
Tatjana I. Cornu

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1130736

4,106 views
15 citations

Policy Brief

Published on 14 Feb 2023

EU regulation of gene-edited plants—A reform proposal

in Genome Editing in Plants

Brigitte Voigt

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1119442

5,782 views
9 citations

Mini Review

Published on 08 Feb 2023

Rare immune diseases paving the road for genome editing-based precision medicine

in Genome Editing in Blood Disorders

Mara Pavel-Dinu
Simon Borna
Rosa Bacchetta

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1114996

3,214 views
5 citations

Original Research

Published on 03 Feb 2023

CRISPR/Cas9 mediated gene editing in non-model nematode Panagrolaimus sp. PS1159

in Genome Editing Tools and Mechanisms

Viktoria Hellekes
Denise Claus
Johanna Seiler
Felix Illner
Philipp H. Schiffer
Michael Kroiher

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1078359

4,298 views
7 citations

Correction

Published on 20 Jan 2023

Corrigendum: CRISPR nuclease off-target activity and mitigation strategies

in Genome Editing in Blood Disorders

Beeke Wienert
M. Kyle Cromer

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1112956

1,230 views
2 citations

Original Research

Published on 20 Jan 2023

On-site and visual detection of sorghum mosaic virus and rice stripe mosaic virus based on reverse transcription-recombinase-aided amplification and CRISPR/Cas12a

in Genome Editing Tools and Mechanisms

Junkai Wang
Xiuqin Huang
Siping Chen
Jiahao Chen
Zhengyi Liang
Biao Chen
Xin Yang
Guohui Zhou
Tong Zhang

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1124794

2,129 views
8 citations

Original Research

Published on 12 Jan 2023

Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits

in Genome Editing in Infectious Diseases

Jenna Kropp Schmidt
Yun Hee Kim
Nick Strelchenko
Sarah R. Gierczic
Derek Pavelec
Thaddeus G. Golos
Igor I. Slukvin

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1031275

3,060 views
2 citations

Mini Review

Published on 11 Jan 2023

Genome editing approaches using reproductive cells/tissues in flowering plants

in Genome Editing in Plants

Erika Toda
Norio Kato
Tetsuya Higashiyama
Takashi Okamoto

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1085023

3,190 views
4 citations

Policy and Practice Reviews

Published on 10 Jan 2023

Are null segregants new combinations of heritable material and should they be regulated?

in Genome Editing in Plants

Jack A. Heinemann
Katrin Clark
Tessa C. Hiscox
Andrew W. McCabe
Sarah Z. Agapito-Tenfen

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1064103

4,573 views
4 citations

Review

Published on 09 Jan 2023

Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders

in Genome Editing in Blood Disorders

Valentina Buffa
José Roberto Alvarez Vargas
Anne Galy
Simone Spinozzi
Céline J. Rocca

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.997142

6,301 views
7 citations

Mini Review

Published on 06 Jan 2023

CRISPR medicine for blood disorders: Progress and challenges in delivery

in Genome Editing in Blood Disorders

Tahereh Mohammadian Gol
Guillermo Ureña-Bailén
Yujuan Hou
Ralph Sinn
Justin S. Antony
Rupert Handgretinger
Markus Mezger

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1037290

6,638 views
8 citations

Original Research

Published on 23 Dec 2022

Efficient hyperactive piggyBac transgenesis in Plodia pantry moths

in Genome Editing Tools and Mechanisms

Christa Heryanto
Anyi Mazo-Vargas
Arnaud Martin

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1074888

2,790 views
4 citations

Original Research

Published on 20 Dec 2022

Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2

in Genome Editing in Blood Disorders

Anila George
Nithin Sam Ravi
Kirti Prasad
Lokesh Panigrahi
Sanya Koikkara
Vignesh Rajendiran
Nivedhitha Devaraju
Joshua Paul
Aswin Anand Pai
Yukio Nakamura

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1085111

5,054 views
1 citation

Review

Published on 08 Dec 2022

Imaging tools for plant nanobiotechnology

in Genome Editing in Plants

Bin Zhao
Zhongxu Luo
Honglu Zhang
Huan Zhang

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1029944

3,839 views
10 citations

Review

Published on 10 Nov 2022

CRISPR nuclease off-target activity and mitigation strategies

in Genome Editing in Blood Disorders

Beeke Wienert
M. Kyle Cromer

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1050507

8,510 views
25 citations

Navigation group

Articles

In search of an ideal template for therapeutic genome editing: A review of current developments for structure optimization

T-CAST: An optimized CAST-Seq pipeline for TALEN confirms superior safety and efficacy of obligate-heterodimeric scaffolds

EU regulation of gene-edited plants—A reform proposal

Rare immune diseases paving the road for genome editing-based precision medicine

CRISPR/Cas9 mediated gene editing in non-model nematode Panagrolaimus sp. PS1159

Corrigendum: CRISPR nuclease off-target activity and mitigation strategies

On-site and visual detection of sorghum mosaic virus and rice stripe mosaic virus based on reverse transcription-recombinase-aided amplification and CRISPR/Cas12a

Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits

Genome editing approaches using reproductive cells/tissues in flowering plants

Are null segregants new combinations of heritable material and should they be regulated?

Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders

CRISPR medicine for blood disorders: Progress and challenges in delivery

Efficient hyperactive piggyBac transgenesis in Plodia pantry moths

Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2

Imaging tools for plant nanobiotechnology

CRISPR nuclease off-target activity and mitigation strategies