Frontiers in Genome Editing

Original Research

Published on 15 Jun 2021

In-planta Gene Targeting in Barley Using Cas9 With and Without Geminiviral Replicons

in Genome Editing in Plants

Tom Lawrenson
Alison Hinchliffe
Martha Clarke
Yvie Morgan
Wendy Harwood

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.663380

6,492 views
12 citations

Correction

Published on 17 May 2021

Corrigendum: Targeted Gene Delivery: Where to Land

in Genome Editing in Blood Disorders

Giulia Pavani
Mario Amendola

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.682171

2,465 views
6 citations

Original Research

Published on 12 May 2021

Efficient Targeted Mutagenesis Mediated by CRISPR-Cas12a Ribonucleoprotein Complexes in Maize

in Genome Editing in Plants

Shujie Dong
Yinping Lucy Qin
Christopher A. Vakulskas
Michael A. Collingwood
Mariam Marand
Stephen Rigoulot
Ling Zhu
Yaping Jiang
Weining Gu
Chunyang Fan

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.670529

7,725 views
20 citations

Brief Research Report

Published on 12 May 2021

CRISPR-Editing of Sweet Basil (Ocimum basilicum L.) Homoserine Kinase Gene for Improved Downy Mildew Disease Resistance

in Genome Editing in Plants

Xiaoyu Zhang
Yee Chen Low
Michael A. Lawton
James E. Simon
Rong Di

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.629769

5,101 views
16 citations

Original Research

Published on 29 Apr 2021

Multiallelic, Targeted Mutagenesis of Magnesium Chelatase With CRISPR/Cas9 Provides a Rapidly Scorable Phenotype in Highly Polyploid Sugarcane

in Genome Editing in Plants

Ayman Eid
Chakravarthi Mohan
Sara Sanchez
Duoduo Wang
Fredy Altpeter

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.654996

11,243 views
72 citations

Review

Published on 31 Mar 2021

Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation

in Genome Editing in Blood Disorders

Samuele Ferrari
Valentina Vavassori
Daniele Canarutto
Aurelien Jacob
Maria Carmina Castiello
Attya Omer Javed
Pietro Genovese

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.618378

16,895 views
35 citations

Review

Published on 24 Mar 2021

The Promise and the Hope of Gene Therapy

in Genome Editing in Blood Disorders

Eleni Papanikolaou
Andreas Bosio

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.618346

77,679 views
71 citations

Review

Published on 15 Mar 2021

Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies

in Genome Engineering and Neurologic Disorders

Amy McTague
Giada Rossignoli
Arianna Ferrini
Serena Barral
Manju A. Kurian

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.630600

21,843 views
36 citations

Brief Research Report

Published on 04 Mar 2021

Spelling Changes and Fluorescent Tagging With Prime Editing Vectors for Plants

in Genome Editing in Plants

Li Wang
Hilal Betul Kaya
Ning Zhang
Rhitu Rai
Matthew R. Willmann
Sara C. D. Carpenter
Andrew C. Read
Federico Martin
Zhangjun Fei
Jan E. Leach

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.617553

10,236 views
39 citations

Review

Published on 03 Mar 2021

Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System

in Genome Engineering and Neurologic Disorders

Vasco Meneghini
Marco Peviani
Marco Luciani
Giada Zambonini
Angela Gritti

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.644319

12,207 views
20 citations

Original Research

Published on 25 Feb 2021

Protein Phosphatase 2A Catalytic Subunit PP2A-1 Enhances Rice Resistance to Sheath Blight Disease

in Genome Editing in Plants

Qiu Jun Lin
Jin Chu
Vikranth Kumar
De Peng Yuan
Zhi Min Li
Qiong Mei
Yuan Hu Xuan

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.632136

3,466 views
13 citations

Original Research

Published on 09 Feb 2021

Baboon Envelope Pseudotyped “Nanoblades” Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells

in Genome Editing in Blood Disorders

Alejandra Gutierrez-Guerrero
Maria Jimena Abrey Recalde
Philippe E. Mangeot
Caroline Costa
Ornellie Bernadin
Séverine Périan
Floriane Fusil
Gisèle Froment
Adriana Martinez-Turtos
Adrien Krug

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.604371

17,117 views
37 citations

Review

Published on 04 Feb 2021

A Small Key for a Heavy Door: Genetic Therapies for the Treatment of Hemoglobinopathies

in Genome Editing in Blood Disorders

Hidde A. Zittersteijn
Cornelis L. Harteveld
Stefanie Klaver-Flores
Arjan C. Lankester
Rob C. Hoeben
Frank J. T. Staal
Manuel A. F. V. Gonçalves

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.617780

9,378 views
14 citations

Mini Review

Published on 01 Feb 2021

Breaking Boundaries in the Brain—Advances in Editing Tools for Neurogenetic Disorders

in Genome Engineering and Neurologic Disorders

Bronte A. Coorey
Wendy A. Gold

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.623519

3,385 views
4 citations

Review

Published on 28 Jan 2021

Base and Prime Editing Technologies for Blood Disorders

in Genome Editing in Blood Disorders

Panagiotis Antoniou
Annarita Miccio
Mégane Brusson

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.618406

58,654 views
59 citations

Review

Published on 28 Jan 2021

Using Synthetically Engineered Guide RNAs to Enhance CRISPR Genome Editing Systems in Mammalian Cells

in Genome Editing in Blood Disorders

Daniel Allen
Michael Rosenberg
Ayal Hendel

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.617910

43,996 views
64 citations