Frontiers in Genetics

Review

Accepted on 16 Sep 2025

Epigenetic and Metabolic Reprogramming via Nanotechnology: A Synergistic Approach to Cancer Vaccination in Lung Tumors

in Cancer Genetics and Oncogenomics

Min Xu
Xialin Zhang
Xinlin Yu
Cheng Ma
Xinwei Li
Gang Chen
Gang Yuan
Sheng Lin
Ran Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1666561

Original Research

Published on 16 Sep 2025

Identification and validation of three tumor suppressors associated with the immune response of acute myeloid leukemia

in Cancer Genetics and Oncogenomics

Yueyuan Pan
Guocai Wu
Chenchen Liu
Minggui Chen
Tian Xia
Yonghua Ma
Zhigang Yang
Ruiting Wen

Frontiers in Genetics

doi 10.3389/fgene.2025.1652142

1,554 views

Original Research

Published on 16 Sep 2025

The hidden in plain sight: global, regional, and national trends in the pediatric burden of Klinefelter syndrome, 1990–2021

in Applied Genetic Epidemiology

Guoqian Ma
Yuan Li
Fan Jia

Frontiers in Genetics

doi 10.3389/fgene.2025.1639699

896 views

Original Research

Accepted on 15 Sep 2025

Whole Exome Sequencing Identifies Concurrent LDLR and ABCG8 Mutations in a Saudi Family with Familial hypercholesterolemia and Sitosterolaemia

in Genetics of Common and Rare Diseases

Abdulrahman Hummadi
Dhayf Alrahman Mutawwam
Jumana Y Al-Aama
Fai Alsubhi
NAJI ALJOHANI
Ali J Alhagawy
Turki Algohani
Ebraheem Fallatah
Mohammed Y Daghriry
Rawan K Alharbi

Frontiers in Genetics

doi 10.3389/fgene.2025.1679594

225 views

Original Research

Accepted on 15 Sep 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

in Cancer Genetics and Oncogenomics

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Li Zhang
Yonglin Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

262 views

Original Research

Accepted on 15 Sep 2025

Immune-Molecular Nexus in Reproductive Disorders: Mechanisms Linking POI and RSA

in Computational Genomics

Chen Chen
Xiaolan Zhu
Xinyue Zhang
Subo Zhang
Wenxin Li
Yueqin Liu
Zhao Dan

Frontiers in Genetics

doi 10.3389/fgene.2025.1652519

137 views

Original Research

Accepted on 15 Sep 2025

Analyzes of Haplotypes of TLR2 and TLR3 genes for COVID-19 Prognosis in a Cohort of Professionals who Worked in the 1st Pandemic Wave in Belém-PA, Brazil

in Computational Genomics

Marcos Jessé Abrahão Silva
Luiza Raquel Tapajós Figueira
Daniele Melo Sardinha
Natasha Cristina Oliveira Andrade
Sebastião Kauã De Sousa Bispo
Thiago Augusto Ferreira Dos Anjos
Everaldina Cordeiro dos Santos
Ana Judith Pires Garcia
Luana Nepomuceno Gondim Costa Lima

Frontiers in Genetics

doi 10.3389/fgene.2025.1659269

133 views

Original Research

Accepted on 15 Sep 2025

Prenatal Diagnosis and Molecular Characterization of PKHD1 Variants in two Chinese Fetuses with Caroli Disease/Syndrome

in Genetics of Common and Rare Diseases

Hui Huang
Sheng Zhao
Dan Wang
Shengbao Pan
Fang Liu
Peiwen Chen
Xinlin Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1651306

159 views

Original Research

Published on 15 Sep 2025

Functional characterization of MFSD3 in auditory system and zebrafish embryogenesis

in Genetics of Common and Rare Diseases

Ying Ma
Shi-Wei Qiu
Wei-Qian Wang
Hai-Feng Feng
Lu Zheng
Ge-Ge Wei
Hui-Yi Nie
Jin-Yuan Yang
Yi-Jin Chen
Pu Dai

Frontiers in Genetics

doi 10.3389/fgene.2025.1634493

441 views

Original Research

Published on 15 Sep 2025

Characterization of the phenotype and function of PRELP+ fibroblast subtype in liver metastatic colorectal cancer

in Cancer Genetics and Oncogenomics

Yuting Dai
Xingying Huang
Min Sun
Shiyu Zhang
Weiqiang Yu
Kongwang Hu
Qiang Wu
Qingfa Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615259

550 views

Original Research

Published on 15 Sep 2025

Personalized skin health management and nutrition strategies: a comprehensive study based on genetic polymorphisms and dietary factors

in Genetics of Aging

Jitao Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1624960

737 views

Methods

Published on 15 Sep 2025

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

in Cancer Genetics and Oncogenomics

Yu Zhang
Kai Jia
Yuntong Guo
Xiaole Ma
Tian Yao
Feng Wu
He Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541401

373 views

Opinion

Published on 15 Sep 2025

The potential clinical and public health implications of presymptomatic genetic testing for transthyretin amyloidosis in African American/Black adults in the United States

in Human and Medical Genomics

Inderjeet Bharaj
Simar J. Singh
Juzer Munaim
Harneet Grewal
Sonia Sabrowsky
Andrew Boshara
Marc A. Silver
Katherine H. Brendish
Paul Underwood
Sandesh Dev

Frontiers in Genetics

doi 10.3389/fgene.2025.1658636

1,205 views

Review

Accepted on 12 Sep 2025

Mechanisms of Circular RNAs in Diabetic Cardiomyopathy: Biological Characteristics and Clinical Prospects

in RNA

Yunfei Guan
Quancheng Han
Meng Wang
Jianguo Xu
Xiujuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1665571

479 views

Original Research

Accepted on 12 Sep 2025

LncRNA and mRNA expression characteristic and bioinformatic analysis in Anemic Diabetic Foot Ulcers

in RNA

Jiayu Lin
Jingying Wang
Bo Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1603315

Original Research

Published on 12 Sep 2025

Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning

in Computational Genomics

Lihua Ni
Huabo Li
Juan Du
Ke Zhou
Fugui Zhang
Liankai Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1587274

726 views