Frontiers in Genetics

Original Research

Published on 22 Sep 2025

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Jiaxuan Qin
Lijian Zhang
Bowen Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1543593

343 views

Original Research

Published on 22 Sep 2025

Identification of platelet function-related genes in STEMI patients

in Computational Genomics

Jingjing Zhu
Shuangya Yang
Qing Guo
Yifan Yang
Bei Shi

Frontiers in Genetics

doi 10.3389/fgene.2025.1651794

221 views

Hypothesis and Theory

Published on 22 Sep 2025

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

in Evolutionary and Population Genetics

Todor Chobanov
Svetoslav Stamov
for Bulgarian Academy of Science and Institute for Balkan Studies

Frontiers in Genetics

doi 10.3389/fgene.2025.1610942

2,659 views

Original Research

Published on 22 Sep 2025

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

in Cancer Genetics and Oncogenomics

Xiucheng Jiang
Lan Shi
Mei Zhao
Cui Chen
Tao Tang
Simeng Ji
Bingbing Lv
Lihua Jia
Shuhan Duan
Jinyue Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1643229

330 views

Original Research

Accepted on 19 Sep 2025

Epitranscriptome-wide profiling identifies RNA editing events regulated by ADAR1 that are associated with DNA repair mechanisms in human TK6 cells

in RNA

Akito Yoshida
Yuqian Song
Hotaru Takaine
Sujin Song
Yu-Hsien Hwang-Fu
Zachary Johnson
Kiyoe Ura
Akira Sassa

Frontiers in Genetics

doi 10.3389/fgene.2025.1663827

9,041 views

Case Report

Accepted on 19 Sep 2025

A novel missense variant of FGD5 in a family with Tetralogy of Fallot

in Genetics of Common and Rare Diseases

Rong Xiang
Meng-Wei Liu
Yi Dong
Liping Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1663959

379 views

Original Research

Published on 19 Sep 2025

Deciphering the shared genetic structure between hip osteoarthritis and femoral neck bone mineral density

in Human and Medical Genomics

Jianguo Zhou
Junfu Na
Zongkun Jiang
Xiaoyan Dou
Shixuan Wang
Hongtao Li
Jian Kang

Frontiers in Genetics

doi 10.3389/fgene.2025.1597005

882 views

Original Research

Published on 19 Sep 2025

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

in Cancer Genetics and Oncogenomics

Tianhe Ling
Jiahui Wu
Ling Xiaohao

Frontiers in Genetics

doi 10.3389/fgene.2025.1606111

617 views

Original Research

Published on 19 Sep 2025

A hypergraph neural network for prioritizing Alzheimer’s disease risk genes

in Computational Genomics

Meng Ma
Chao Deng
Yan Liu
Qingqing Cao
Fang Liu
Yan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668200

566 views

Review

Published on 19 Sep 2025

Beyond single references: pangenome graphs and the future of genomic medicine

in Human and Medical Genomics

Denis M. Nyaga
Roan E. Zaied
Olin K. Silander
Michael A. Black
Justin M. O’Sullivan

Frontiers in Genetics

doi 10.3389/fgene.2025.1679660

1,337 views

Original Research

Published on 19 Sep 2025

A novel COL2A1 mutation in a Chinese family with predominantly ocular Stickler syndrome

in Genetics of Common and Rare Diseases

Yanyu Lin
Xin Liu
Shuxian Lin
Jiansheng Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1646923

758 views

Original Research

Accepted on 18 Sep 2025

Sex-Specific Gene Expression and Weighted Co-Expression Network Analysis Suggest Distinct Sex-Specific Molecular Signatures in Acutely Suicidal MDD-Patients Without Somatic Comorbidities

in Behavioral and Psychiatric Genetics

Michael Fritz
Karlheinz Holzmann
Silvia Castany
Heidrun Haas
Christian Montag
David Engblom
Judith Streb
Manuela Dudeck

Frontiers in Genetics

doi 10.3389/fgene.2025.1653768

1,230 views

Policy and Practice Reviews

Accepted on 18 Sep 2025

A Training Program to Extend the Reach of the Deciphering Developmental Disorders in Africa (DDD-Africa) Study

in ELSI in Science and Genetics

Aaliah Charles
Zané Lombard
Nadia Carstens
Zandisiwe Goliath
Aimé Lumaka
Prince Makay
Nadja Louw
Robyn Kerr
Amanda Krause
Koenraad Devriendt

Frontiers in Genetics

doi 10.3389/fgene.2025.1611047

405 views

Original Research

Accepted on 18 Sep 2025

Prenatal Diagnosis of Prader-Willi Syndrome via Maternal UPD15 with Placental Mosaicism: Incidental Discovery of Fetal DMD Carrier Status

in Genetics of Common and Rare Diseases

Yanchou Ye
Yiman Fu
Zhechao Zhang
Haofeng Ning
Fangchao Tao
Xiaonan Wang
Qun Fang
Zheng Chen
Xiulan Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1675663

444 views

Original Research

Published on 18 Sep 2025

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

in Cancer Genetics and Oncogenomics

Bin Yu
Shu-Yan Zhao
Yun-Hua Zhu
Jun-Jie Luo
Ke Zheng
Bin-Jie Shen
Yi-Lin Shen
Huan-Xin Zhong

Frontiers in Genetics

doi 10.3389/fgene.2025.1605385

758 views

Original Research

Published on 18 Sep 2025

Genome-wide association analysis of resistance to bacterial cold-water disease in an important rainbow trout aquaculture breeding population

in Livestock Genomics

Bruna Santana
Yniv Palti
Guangtu Gao
Vibha Tripathi
Kyle E. Martin
Breno O. Fragomeni

Frontiers in Genetics

doi 10.3389/fgene.2025.1582138

738 views