Frontiers in Genetics

Original Research

Published on 25 Mar 2025

Novel variations in the PLOD1, COL1A1, COL5A2 and COL4A1 genes related to keratoconus

in Genetics of Common and Rare Diseases

Qinghong Lin
Xuejun Wang
Xiaoliao Peng
Tian Han
Ling Sun
Xiaoyu Zhang
Xingtao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1497915

2,658 views
1 citation

Review

Published on 24 Mar 2025

Genetic diversity, reproductive performance, and genetic enhancement strategies in Huang-Huai goats

in Livestock Genomics

Kai Quan
Huibin Shi
Caihong Wei
Jun Li
Kun Liu
Huihua Wang
Wei Sun
Haoyuan Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1549051

3,361 views
3 citations

Original Research

Published on 24 Mar 2025

Multi-trait phenotypic modeling through factor analysis and bayesian network learning to develop latent reproductive, body conformational, and carcass-associated traits in admixed beef heifers

in Livestock Genomics

Muhammad Anas
Bin Zhao
Haipeng Yu
Carl R. Dahlen
Kendall C. Swanson
Kris A. Ringwall
Lauren L. Hulsman Hanna

Frontiers in Genetics

doi 10.3389/fgene.2025.1551967

2,944 views
1 citation

Original Research

Published on 24 Mar 2025

Construction of a risk model associated with tryptophan metabolism and identification of related molecular subtypes in laryngeal squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Feng Liu
Yanchao Qin
Wei Luo
XianHui Ruan
Lifang Lu
Bowei Feng
Jianfei Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1530334

2,936 views
1 citation

Brief Research Report

Published on 24 Mar 2025

Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan

in Evolutionary, Population, and Conservation Genetics

Aigul Zhunussova
Saltanat Tayshanova
Alizhan Bukayev
Ayagoz Bukayeva
Baglan Aidarov
Radik Temirgaliev
Zhaxylyk Sabitov
Maxat Zhabagin

Frontiers in Genetics

doi 10.3389/fgene.2025.1516130

8,170 views

Original Research

Published on 21 Mar 2025

A semi-supervised weighted SPCA- and convolution KAN-based model for drug response prediction

in Computational Genomics

Rui Miao
Bing-Jie Zhong
Xin-Yue Mei
Xin Dong
Yang-Dong Ou
Yong Liang
Hao-Yang Yu
Ying Wang
Zi-Han Dong

Frontiers in Genetics

doi 10.3389/fgene.2025.1532651

3,135 views
1 citation

Original Research

Published on 21 Mar 2025

Assessment of physician preparedness for implementation of pathology-supported genetic testing: solution-driven post-COVID-19 survey

in Human and Medical Genomics

Elouise E. Kroon
Yolandi Swart
Chantelle J. Scott
Denise Scholtz
Daniel W. Olivier
Kelebogile E. Moremi
Chantelle Venter
Maxine Waters
Sunday O. Oladejo
Craig J. Kinnear

Frontiers in Genetics

doi 10.3389/fgene.2025.1543056

2,917 views

Original Research

Published on 21 Mar 2025

Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis

in Computational Genomics

Xiu-De Qin
Yue-Rong Li
Qian Cai
Jia-Ye Liu
Zhao-Hui Dang
Li-Ling Li
Jia-Wei Min
Shao-Hua Qi
Fan Bu

Frontiers in Genetics

doi 10.3389/fgene.2025.1479270

5,379 views

Original Research

Published on 21 Mar 2025

Cancer classification in high dimensional microarray gene expressions by feature selection using eagle prey optimization

in Computational Genomics

Swetha Dhamercherla
Damodar Reddy Edla
Suresh Dara

Frontiers in Genetics

doi 10.3389/fgene.2025.1528810

2,435 views
6 citations

Original Research

Published on 20 Mar 2025

Identified five variants in CFTR gene that alter RNA splicing by minigene assay

in Genetics of Common and Rare Diseases

Bingying Zhang
Yiyin Zhang
Yan Zhang
Xuyan Liu
Ran Zhang
Zhi Wang
Fengjiao Pan
Ning Xu
Leping Shao

Frontiers in Genetics

doi 10.3389/fgene.2025.1543623

4,212 views
2 citations

Original Research

Published on 20 Mar 2025

MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction

in Computational Genomics

Xu Gao
Mengfan Yan
Chengwei Zhang
Gang Wu
Jiandong Shang
Congxiang Zhang
Kecheng Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1527300

3,170 views
2 citations

Original Research

Published on 20 Mar 2025

Effects of drought pretreatment on the morphology traits, biomass, and stoichiometric characteristics of the desert ephemeral plant

in Genomics of Plants and Plant-Associated Organisms

Qian Liu
Hongmin Li
Chen Gong
Qianli Zhang
Tao Pan
Zhaodan Cao
Yanfeng Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1534894

1,867 views

Original Research

Published on 20 Mar 2025

A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis

in RNA

Yutong Wei
Zilu Wen
Qinghua Xue
Lin Wang
Hui Chen
Lei Shi
Laiyi Wan
Leilei Li
Hongwei Li
Wentao Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1544007

3,344 views
2 citations

Original Research

Published on 20 Mar 2025

Causal relationships between serum metabolites and coronary heart disease risk: a mendelian randomization study

in Statistical Genetics and Methodology

Xiao-Yan Meng
Yong-Qing Zhu
Ying-Jie Zhang
Wei Sun
Shu-Ang Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1440364

3,158 views
1 citation

Original Research

Published on 19 Mar 2025

Enhancing wheat β-glucan content through precision crossbreeding: development and evaluation of biofortified lines with improved nutritional and agronomic traits

in Genomics of Plants and Plant-Associated Organisms

Upendra Kumar
Sourav Panigrahi
Rita Goswami
Yogita Singh
Priyanka Balyan
Prexha Kapoor
Sundip Kumar
Krishna Pal Singh
Farkhandah Jan
Reyazul Rouf Mir

Frontiers in Genetics

doi 10.3389/fgene.2025.1532956

2,264 views
1 citation

Original Research

Published on 19 Mar 2025

Identification of key genes in periodontitis

in Computational Genomics

Xianyang Cheng
Shan Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1579848

3,560 views
5 citations

Review

Published on 19 Mar 2025

Review of the role and potential clinical value of m6A methylation modifications in the biological process of osteosarcoma

in Epigenomics and Epigenetics

Huaqiang Zhou
Rongbing Shu
Jianming Wu
Jiangjun Zhou
Zhuanyi Yu
Qiuxin Cheng
Zhihao Peng
Min Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1522622

2,999 views
1 citation

Original Research

Published on 19 Mar 2025

Clinical genetic analysis of an adult polyglucosan body disease (APBD) family caused by the compound heterozygous variant of GBE1 p.R156C and deletion exon 3-7

in Genetics of Common and Rare Diseases

Juan Zhu
Hong-Ping Yu
Jing Zou
Yi-Wu Zhang
Xin-Qi Han
Zi-Yan Xu
Li Chen
Qian Chen
Mei-Zhu Gao
Li-Jun Xie

Frontiers in Genetics

doi 10.3389/fgene.2025.1514610

3,010 views
1 citation

Editorial

Published on 19 Mar 2025

Editorial: Functional study of novel VUS (variant of uncertain significance) mutations in single-gene inherited disease

in Statistical Genetics and Methodology

Guohua Yang
Hua Zhong
Huiliang Wen
Yiping Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1578736

3,384 views

Original Research

Published on 19 Mar 2025

Functional analysis of a novel FBN1 deep intronic variant causing Marfan syndrome in a Chinese patient

in Human and Medical Genomics

Qingming Wang
Fang Zhang
Xinlong Zhou
Hui Li
Juan Zhao
Haiming Yuan

Frontiers in Genetics

doi 10.3389/fgene.2025.1564824

2,507 views

Original Research

Published on 19 Mar 2025

Multi-tissue transcriptomic characterization of endogenous retrovirus-derived transcripts in Capra hircus

in Livestock Genomics

Ming-Di Li
Hu-Rong Li
Shao-Hui Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1544330

2,289 views

Original Research

Published on 19 Mar 2025

Mechanism of action and experimental validation of key genes common to diabetic retinopathy and coronary heart disease based on multiple bioinformatics investigations

in Computational Genomics

Fanli Jiang
Shi Yin
Xinjin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1548147

2,443 views

Mini Review

Published on 19 Mar 2025

Congenital heart disease presentations in the 15q11.2 microdeletion syndrome

in Genetics of Common and Rare Diseases

Claudia-Ioana Fifirig
Sabu Abraham
Bernard Keavney
Kathryn E. Hentges

Frontiers in Genetics

doi 10.3389/fgene.2025.1535732

6,635 views

Case Report

Published on 19 Mar 2025

Case report: Inflammatory bowel disease in Hermansky-Pudlak syndrome type 3 due to novel variant in HPS3

in Genetics of Common and Rare Diseases

Jingqun Mai
Zhu Zhang
Bocheng Xu
Shanling Liu
He Wang
Hao Wang
Shuo Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1465527

2,097 views
1 citation

16,801 articles

articles

Novel variations in the PLOD1, COL1A1, COL5A2 and COL4A1 genes related to keratoconus

Genetic diversity, reproductive performance, and genetic enhancement strategies in Huang-Huai goats

Multi-trait phenotypic modeling through factor analysis and bayesian network learning to develop latent reproductive, body conformational, and carcass-associated traits in admixed beef heifers

Construction of a risk model associated with tryptophan metabolism and identification of related molecular subtypes in laryngeal squamous cell carcinoma

Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan

A semi-supervised weighted SPCA- and convolution KAN-based model for drug response prediction

Assessment of physician preparedness for implementation of pathology-supported genetic testing: solution-driven post-COVID-19 survey

Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis

Cancer classification in high dimensional microarray gene expressions by feature selection using eagle prey optimization

Identified five variants in CFTR gene that alter RNA splicing by minigene assay

MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction

Effects of drought pretreatment on the morphology traits, biomass, and stoichiometric characteristics of the desert ephemeral plant

A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis

Causal relationships between serum metabolites and coronary heart disease risk: a mendelian randomization study

Enhancing wheat β-glucan content through precision crossbreeding: development and evaluation of biofortified lines with improved nutritional and agronomic traits

Identification of key genes in periodontitis

Review of the role and potential clinical value of m6A methylation modifications in the biological process of osteosarcoma

Clinical genetic analysis of an adult polyglucosan body disease (APBD) family caused by the compound heterozygous variant of GBE1 p.R156C and deletion exon 3-7

Editorial: Functional study of novel VUS (variant of uncertain significance) mutations in single-gene inherited disease

Functional analysis of a novel FBN1 deep intronic variant causing Marfan syndrome in a Chinese patient

Multi-tissue transcriptomic characterization of endogenous retrovirus-derived transcripts in Capra hircus

Mechanism of action and experimental validation of key genes common to diabetic retinopathy and coronary heart disease based on multiple bioinformatics investigations

Congenital heart disease presentations in the 15q11.2 microdeletion syndrome

Case report: Inflammatory bowel disease in Hermansky-Pudlak syndrome type 3 due to novel variant in HPS3