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EDITORIAL article

Front. Genet.
Sec. RNA
Volume 15 - 2024 | doi: 10.3389/fgene.2024.1513211
This article is part of the Research Topic Non-Coding RNAs and Human Diseases Volume 2 -Long Non-Coding RNAs (lncRNAs) and Pathogenesis of Human Disease View all 16 articles

Editorial for the Research Topic: "Non-Coding RNAs and Human Diseases Volume 2 -Long Non-Coding RNAs (lncRNAs) and Pathogenesis of Human Disease" for Frontiers in Genetics

Provisionally accepted
Yujing Li Yujing Li 1,2*Shunliang Xu Shunliang Xu 3*Liqi Shu Liqi Shu 4,5*Cuida Meng Cuida Meng 6*Zhao-Qian Teng Zhao-Qian Teng 7*
  • 1 Emory University, Atlanta, United States
  • 2 School of Medicine, Emory University, Atlanta, Georgia, United States
  • 3 The Second Hospital Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
  • 4 Rhode Island Hospital, Providence, Rhode Island, United States
  • 5 Rhode Island Space Grant Consortium, Brown University, Providence, Rhode Island, United States
  • 6 China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China
  • 7 Institute of Zoology, Chinese Academy of Sciences (CAS), Beijing, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Long non-coding RNAs (lncRNAs), a class of typically non-translatable transcripts with length of 200 nucleotides or longer, have attracted significant attention within the expansive realm of ncRNA research. Distinct from their smaller counterparts-such as microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs)-lncRNAs exhibit a unique regulatory capacity, influencing critical biological processes and pathologies. Around 30,000 lncRNAs identified within human tissues exhibit remarkable tissue-specific expression patterns, suggesting their potential as biomarkers and therapeutic targets. The 2 nd volume of our research topic, "Non-Coding RNAs and Human Diseases," focused on the roles of lncRNAs in various human diseases, particularly on their involvement in the pathogenesis of neurological disorders, cancers, cardiac, lung, and liver diseases. In summary, this volume presents a rich tapestry of research highlighting the significance of lncRNAs as biomarkers for diagnosis and prognosis, as well as potential therapeutic targets across a spectrum of human diseases. The findings and discussions within these articles aim to provide valuable insights for researchers and clinical physicians, fostering a deeper understanding of lncRNAs in health and disease. We hope that this compilation of knowledge serves as a useful resource for advancing research and clinical applications in the field of noncoding RNAs and their significance in human health and disease.

    Keywords: long non-coding RNA, Human Disease, Epigenetic marker, therapy, Pathogenesis, Transcriptome

    Received: 18 Oct 2024; Accepted: 21 Oct 2024.

    Copyright: © 2024 Li, Xu, Shu, Meng and Teng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yujing Li, Emory University, Atlanta, United States
    Shunliang Xu, The Second Hospital Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
    Liqi Shu, Rhode Island Hospital, Providence, 02903, Rhode Island, United States
    Cuida Meng, China-Japan Union Hospital, Jilin University, Changchun, 130033, Jilin Province, China
    Zhao-Qian Teng, Institute of Zoology, Chinese Academy of Sciences (CAS), Beijing, 100101, Beijing Municipality, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.