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EDITORIAL article

Front. Genet.
Sec. Computational Genomics
Volume 15 - 2024 | doi: 10.3389/fgene.2024.1512594
This article is part of the Research Topic Emerging Talents in Computational Genomics View all 5 articles

Editorial: Emerging Talents in Computational Genomics

Provisionally accepted
  • 1 University of Michigan, Ann Arbor, United States
  • 2 The University of Tokyo, Bunkyo, Tōkyō, Japan

The final, formatted version of the article will be published soon.

    The aim of this special issue, 'Emerging Talents in Computational Genomics' at Frontiers in Genetics, was to highlight the emerging talents of student researchers in computational genomics and give them opportunities to get involved in journal editorial processes. Behind this initiative, the journal was aware that results from most student-driven research projects are not much shared with a broader audience, while many students are undertaking research in computational genomics as part of their educational programs. Therefore, we invited student researchers to this special issue at the Frontiers, providing them with hands-on guidance and constructive feedback.As briefly summarized below, the authors successfully shared scientific findings from their research projects.Mendapara et al. [1] introduced a novel gene-based prediction model for detecting chronic kidney disease, utilizing gene expression profiling datasets from the Gene Expression Omnibus (GEO) database. The model, constructed and optimized using a training dataset, was further validated with another dataset. This study identified genetic biomarkers for chronic kidney disease risk, which makes a significant contribution to the field. Kabir et al. [2] delved into the interactions between human and Candida albicans proteins in oral candidiasis, using datasets from the Human Protein-Candida albicans Interaction Database. The authors identified corresponding human proteins by mapping differentially expressed genes in patients with Candida albicans. This study not only provided a molecular map of the host-pathogen interaction in oral candidiasis but also potential targets for therapeutic intervention.Rockenbach et al. [3] analyzed transcriptome data from the human ovary and testis during the prenatal period and adulthood to study the role of gametes in sex-specific events such as oogenesis and spermatogenesis. The authors found that meiosis-related genes were differentially expressed in female and male gonads and gametes between normal and pathological conditions. These findings shed light on new candidate genes involved in human fertility disorders.Chaudhari et al. [4] reviewed the history of the development of microbe culture-independent molecular methods of metagenomics and reviewed techniques, data analyses, and data interpretation and representation.Overall, the original research and review articles presented in this special issue underscore the importance of student-driven studies in computational genomics. As Topic Editors, we extend our heartfelt thanks to all the contributors for their invaluable peer-review processes and collaborative efforts, which we deeply appreciate. We believe this Research Topic will help identify talented students and allow the community to follow the promising careers of these emerging, talented researchers.Author contributions JI and KN: Writing-original draft, edit, and final approval. The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.

    Keywords: Computational genomics, gene-based prediction model, Host-pathogen interaction genetics, transcriptome data analyses, Metagenomics

    Received: 17 Oct 2024; Accepted: 21 Oct 2024.

    Copyright: © 2024 Iwata and Nakai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Junichi Iwata, University of Michigan, Ann Arbor, United States
    Kenta Nakai, The University of Tokyo, Bunkyo, 113-8654, Tōkyō, Japan

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.