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SYSTEMATIC REVIEW article

Front. Genet.
Sec. Human and Medical Genomics
Volume 15 - 2024 | doi: 10.3389/fgene.2024.1481948
This article is part of the Research Topic Insights in Human and Medical Genomics 2024 View all articles

Consumer-oriented (patient and family) outcomes from nursing in genomics: A scoping review of the literature (2012-2022)

Provisionally accepted
Jordan N Keels Jordan N Keels 1Joanne Thomas Joanne Thomas 2Kathleen Anne Calzone Kathleen Anne Calzone 3Laurie Badzek Laurie Badzek 4Sarah Dewell Sarah Dewell 5Vinaya Murthy Vinaya Murthy 6Rosie O'shea Rosie O'shea 7Emma T Tonkin Emma T Tonkin 2Andrew A. Dwyer Andrew A. Dwyer 1*
  • 1 Boston College, Chestnut Hill, United States
  • 2 University of South Wales, Treforest, United Kingdom
  • 3 National Cancer Institute (NIH), Rockville, Maryland, United States
  • 4 The Pennsylvania State University (PSU), University Park, Pennsylvania, United States
  • 5 Thompson Rivers University, Kamloops, British Columbia, Canada
  • 6 School of Medicine, University of California San Francisco, San Francisco, California, United States
  • 7 Trinity College Dublin, Dublin, County Dublin, Ireland

The final, formatted version of the article will be published soon.

    Genomics is a lifespan competency that is important for improving health outcomes for individuals, families and communities. Nurses play a key role in genomic healthcare and realizing the potential of the genomic era. We aimed to chart the current state of genomics in nursing by conducting a systematic scoping review of the literature in four databases (2012)(2013)(2014)(2015)(2016)(2017)(2018)(2019)(2020)(2021)(2022). We categorized included articles using the Cochrane Collaboration outcome domains/sub-domains and identify key topical areas. Of 8532 retrieved articles, we identified 67 articles on 'consumer-oriented outcomes' (patient and family) for analysis. Identified articles primarily centered on themes of genetic testing and screening. Most studies reported non-interventional studies 39/67 (58%) and more than half were from the U.S.A. 34/67 (51%). Six of nine subdomains were reported on. The "patient involvement in care" subdomain was the most commonly reported subdomain (17/67, 25%) while "treatment outcomes" had the fewest reports (5/67, 8%). Overall, consumers (i.e., patients and families) had high satisfaction with nurse-led interventions. Synthesizing findings revealed key knowledge gaps and unmet patient informational needs around genetic testing and decision support.There are opportunities for interprofessional collaboration between nursing and genetic counseling to meet the mounting demand for genomic healthcare and develop more person-centered approaches to genetic counseling and decisional support. Findings support the need for interventional studies and enhanced focus on implementation for nurses to improve consumer-oriented outcomes.

    Keywords: Cascade screening, Decision Making, family history, Genetic Counseling, Genetic Testing, nursing practice, Oncology Nursing, precision healthcare

    Received: 16 Aug 2024; Accepted: 19 Nov 2024.

    Copyright: © 2024 Keels, Thomas, Calzone, Badzek, Dewell, Murthy, O'shea, Tonkin and Dwyer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Andrew A. Dwyer, Boston College, Chestnut Hill, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.