Identification of MicroRNA-92a-3p as an Essential Regulator of Tubular Epithelial Cell Pyroptosis by Targeting Nrf1 via HO-1
- 1Department of Traditional Chinese Medicine, Qingdao Municipal Hospital, Qingdao University, Qingdao, China
- 2Department of Urology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China
A Corrigendum on
Identification of microRNA-92a-3p as an essential regulator of tubular epithelial cell pyroptosis by targeting Nrf1 via HO-1
by Wang R, Zhao H, Zhang Y, Zhu H, Su Q, Qi H, Deng J and Xiao C (2021). Front. Genet. 11:616947. doi: 10.3389/fgene.2020.616947
In the published article, there was an error in Figure 5A as published. A visual field of IL-18 staining in Sham antagomir NC group was misplaced in the Sham antagomir miR-92a-3p group, when assembled. The corrected Figure 5 is given below.
![www.frontiersin.org](https://www.frontiersin.org/files/Articles/1272660/fgene-14-1272660-HTML-r1/image_m/fgene-14-1272660-g005.jpg)
FIGURE 5. The inhibition of miR-92a-3p alleviated TEC pyroptosis in I/R-induced kidney of mice. (A) Representative photomicrographs of tubular cell injury in mouse kidney tissue sections with HE staining, TUNEL staining, and representative photomicrographs of IL-1β and IL-18 expression in mouse kidney tissue sections by immunohistochemistry, 400×, scale bar = 20 µm. (B) Statistical quantification analysis showed the injury score of HE staining in the kidney tissues. (C) Statistical analysis showed the percentage of TUNEL-positive TECs in the kidney tissues. (D) Statistical analysis showed the positive area of IL-1β and IL-18 in the kidney tissues. (E,F) Western blot analysis of Nrf1, GSDMD-N, NLRP3, and caspase-1 expression in mouse kidney tissue sections. SCr levels (G) and BUN levels (H) were detected in mice. Data are expressed as the mean ± SD. n = 5 per group. *P < 0.05 vs. antagomir NC sham group. ∧P > 0.05 vs. antagomir NC sham group. #P < 0.05 vs. I/R-induced antagomir NC group, one-way ANOVA.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: renal ischemia–reperfusion injury, miR-92a-3p, Nrf1, pyroptosis, tubular epithelial cell, HO-1
Citation: Wang R, Zhao H, Zhang Y, Zhu H, Su Q, Qi H, Deng J and Xiao C (2023) Corrigendum: Identification of microRNA-92a-3p as an essential regulator of tubular epithelial cell pyroptosis by targeting Nrf1 via HO-1. Front. Genet. 14:1272660. doi: 10.3389/fgene.2023.1272660
Received: 04 August 2023; Accepted: 03 October 2023;
Published: 01 November 2023.
Edited and reviewed by:
Naoyuki Kataoka, The University of Tokyo, JapanCopyright © 2023 Wang, Zhao, Zhang, Zhu, Su, Qi, Deng and Xiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Chengcheng Xiao, doc_xiaocc@163.com
†These authors have contributed equally to this work