AUTHOR=Zheng Xinchang , Zong Wenting , Li Zhaohua , Ma Yingke , Sun Yanling , Xiong Zhuang , Wu Song , Yang Fei , Zhao Wei , Bu Congfan , Du Zhenglin , Xiao Jingfa , Bao Yiming TITLE=CCAS: One-stop and comprehensive annotation system for individual cancer genome at multi-omics level JOURNAL=Frontiers in Genetics VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.956781 DOI=10.3389/fgene.2022.956781 ISSN=1664-8021 ABSTRACT=
Due to the explosion of cancer genome data and the urgent needs for cancer treatment, it is becoming increasingly important and necessary to easily and timely analyze and annotate cancer genomes. However, tumor heterogeneity is recognized as a serious barrier to annotate cancer genomes at the individual patient level. In addition, the interpretation and analysis of cancer multi-omics data rely heavily on existing database resources that are often located in different data centers or research institutions, which poses a huge challenge for data parsing. Here we present CCAS (Cancer genome Consensus Annotation System,