AUTHOR=Wang Ying , Xiong Fei , Song Zhaobin 

TITLE=Molecular Phylogeny and Adaptive Mitochondrial DNA Evolution of Salmonids (Pisces: Salmonidae)

JOURNAL=Frontiers in Genetics

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.903240

DOI=10.3389/fgene.2022.903240

ISSN=1664-8021

ABSTRACT=<p>Salmonids are composed of anadromous and freshwater fishes, which is an important model for studying adaptive evolution. Herein, 49 salmonid complete mitochondrial genomes and those of two outgroups were used to infer a robust phylogeny for the family Salmonidae. The BI and RAxML phylogenetic trees based on 13 concatenated mitochondrial protein-coding genes showed well-supported nodes, and topologies were highly congruent. The concatenated 13 mitochondrial protein-coding genes, <italic>ND2</italic>, <italic>ND3</italic>, and <italic>ND5</italic> genes were shown to have significantly larger <italic>dN/dS</italic> ratios in anadromous species than in freshwater species of Salmonidae, but the <italic>CYTB</italic> gene had significantly smaller <italic>dN/dS</italic> in anadromous species. The FEL analysis identified positively selected sites and negatively selected sites in each mitochondrial protein-coding gene separately. The RELAX program revealed that the <italic>ATP8</italic> and <italic>CYTB</italic> genes supported intensified selection of the anadromous lineages. Our results demonstrated the phylogeny of Salmonidae and explored the mitochondrial DNA evolution pattern between anadromous and freshwater salmonids.</p>