AUTHOR=Yuan Lin , Yang Zhenyu , Zhao Jing , Sun Tao , Hu Chunyu , Shen Zhen , Yu Guanying 

TITLE=Pan-Cancer Bioinformatics Analysis of Gene UBE2C

JOURNAL=Frontiers in Genetics

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.893358

DOI=10.3389/fgene.2022.893358

ISSN=1664-8021

ABSTRACT=<p>Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.</p>