AUTHOR=Liu Yinbo , Shen Yingying , Wang Hong , Zhang Yong , Zhu Xiaolei TITLE=m5Cpred-XS: A New Method for Predicting RNA m5C Sites Based on XGBoost and SHAP JOURNAL=Frontiers in Genetics VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.853258 DOI=10.3389/fgene.2022.853258 ISSN=1664-8021 ABSTRACT=
As one of the most important post-transcriptional modifications of RNA, 5-cytosine-methylation (m5C) is reported to closely relate to many chemical reactions and biological functions in cells. Recently, several computational methods have been proposed for identifying m5C sites. However, the accuracy and efficiency are still not satisfactory. In this study, we proposed a new method, m5Cpred-XS, for predicting m5C sites of