AUTHOR=Fernandez-Diaz Daniel , Rodriguez-Vidal Cristina , Silva-Rodríguez Paula , Paniagua Laura , Blanco-Teijeiro María José , Pardo María , Piñeiro Antonio , Bande Manuel 

TITLE=Applications of Non-Coding RNAs in Patients With Retinoblastoma

JOURNAL=Frontiers in Genetics

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.842509

DOI=10.3389/fgene.2022.842509

ISSN=1664-8021

ABSTRACT=<p>Retinoblastoma (RB) is the most common primary intraocular malignancy in childhood. In the carcinogenic process of neoplasms such as RB, the role of non-coding RNAs (ncRNAs) has been widely demonstrated recently. In this review, we aim to provide a clinical overview of the current knowledge regarding ncRNAs in relation to RB. Although ncRNAs are now considered as potential diagnostic biomarkers, prognostic factors, and therapeutic targets, further studies will facilitate enhanced understanding of ncRNAs in RB physiopathology and define the roles ncRNAs can play in clinical practice.</p>