AUTHOR=Zeng Yunqing , Rong Huimin , Xu Jianwei , Cao Ruyue , Li Shuhua , Gao Yanjing , Cheng Baoquan , Zhou Tao 

TITLE=DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer

JOURNAL=Frontiers in Genetics

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.823905

DOI=10.3389/fgene.2022.823905

ISSN=1664-8021

ABSTRACT=<p>Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence and development are closely related to epigenetic modifications. Methylation of DNA before or during gastric cancer is an interesting research topic. This article reviews the studies on DNA methylation related to the cause, diagnosis, treatment, and prognosis of gastric cancer and aims to find cancer biomarkers to solve major human health problems.</p>