AUTHOR=Li Jie , Wang Tao , Liu Wei , Yin Danqing , Lai Zhengqing , Zhang Guosong , Zhang Kai , Ji Jie , Yin Shaowu 

TITLE=A high-quality chromosome-level genome assembly of Pelteobagrus vachelli provides insights into its environmental adaptation and population history

JOURNAL=Frontiers in Genetics

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.1050192

DOI=10.3389/fgene.2022.1050192

ISSN=1664-8021

ABSTRACT=<p><italic>Pelteobagrus vachelli</italic> is a freshwater fish with high economic value, but the lack of genome resources has severely restricted its industrial development and population conservation. Here, we constructed the first chromosome-level genome assembly of <italic>P. vachelli</italic> with a total length of approximately 662.13 Mb and a contig N50 was 14.02 Mb, and scaffolds covering 99.79% of the assembly were anchored to 26 chromosomes. Combining the comparative genome results and transcriptome data under environmental stress (high temperature, hypoxia and <italic>Edwardsiella. ictaluri</italic> infection), the MAPK signaling pathway, PI3K-Akt signaling pathway and apelin signaling pathway play an important role in environmental adaptation of <italic>P. vachelli</italic>, and these pathways were interconnected by the ErbB family and involved in cell proliferation, differentiation and apoptosis. Population evolution analysis showed that artificial interventions have affected wild populations of <italic>P. vachelli</italic>. This study provides a useful genomic information for the genetic breeding of <italic>P. vachelli</italic>, as well as references for further studies on fish biology and evolution.</p>