AUTHOR=Diao Jian , Li Shuxuan , Ma Ling , Zhang Ping , Bai Jianyang , Wang Jiaqi , Ma Xiaoqian , Ma Wei 

TITLE=Genome-Wide Analysis of Major Facilitator Superfamily and Its Expression in Response of Poplar to Fusarium oxysporum

JOURNAL=Frontiers in Genetics

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.769888

DOI=10.3389/fgene.2021.769888

ISSN=1664-8021

ABSTRACT=<p>The major facilitator superfamily (MFS) is one of the largest known membrane transporter families. MFSs are involved in many essential functions, but studies on the MFS family in poplar have not yet been reported. Here, we identified 41 <italic>MFS</italic> genes from <italic>Populus trichocarpa</italic> (<italic>PtrMFSs</italic>). We built a phylogenetic tree, which clearly divided members of PtrMFS into six groups with specific gene structures and protein motifs/domains. The promoter regions contain various cis-acting elements involved in stress and hormone responsiveness. Genes derived from segmental duplication events are unevenly distributed in 17 poplar chromosomes. Collinearity analysis showed that <italic>PtrMFS</italic> genes are conserved and homologous to corresponding genes from four other species. Transcriptome data indicated that 40 poplar <italic>MFS</italic> genes were differentially expressed when treated with <italic>Fusarium oxysporum</italic>. Co-expression networks and gene function annotations of <italic>MFS</italic> genes showed that <italic>MFS</italic> genes tightly co-regulated and closely related in function of transmembrane transport. Taken together, we systematically analyzed structure and function of genes and proteins in the PtrMFS family. Evidence indicated that poplar <italic>MFS</italic> genes play key roles in plant development and response to a biological stressor.</p>