AUTHOR=Liu Wensheng , Zhao Yinan , Liu Xiaohua , Zhang Xiaoya , Ding Jiancheng , Li Yang , Tian Yingpu , Wang Haibin , Liu Wen , Lu Zhongxian TITLE=A Novel Meiosis-Related lncRNA, Rbakdn, Contributes to Spermatogenesis by Stabilizing Ptbp2 JOURNAL=Frontiers in Genetics VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.752495 DOI=10.3389/fgene.2021.752495 ISSN=1664-8021 ABSTRACT=
Spermatocyte meiosis is the cornerstone of mammalian production. Thousands of long noncoding RNAs (lncRNAs) have been reported to be functional in various cellular processes, but the function of lncRNAs in meiosis remains largely unknown. Here, we profiled lncRNAs in spermatocytes at stage I of meiosis and identified a testis-specific lncRNA, Rbakdn, as a vital regulator of meiosis. Rbakdn is dynamically expressed during meiosis I, and Rbakdn knockdown inhibits meiosis