AUTHOR=Booth Kevin T. , Hirsch Yoel , Vardaro Anna C. , Ekstein Josef , Yefet Devorah , Quint Adina , Weiden Tzvi , Corey David P. TITLE=Identification of Novel and Recurrent Variants in MYO15A in Ashkenazi Jewish Patients With Autosomal Recessive Nonsyndromic Hearing Loss JOURNAL=Frontiers in Genetics VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.737782 DOI=10.3389/fgene.2021.737782 ISSN=1664-8021 ABSTRACT=
Hearing loss is a genetically and phenotypically heterogeneous disorder. The purpose of this study was to determine the genetic cause underlying hearing loss in four Ashkenazi Jewish families. We screened probands from each family using a combination of targeted mutation screening and exome sequencing to identifiy the genetic cause of hearing loss in each family. We identified four variants in