AUTHOR=Yousaf Aisha , Liu Junfeng , Ye Sicheng , Chen Hua TITLE=Current Progress in Evolutionary Comparative Genomics of Great Apes JOURNAL=Frontiers in Genetics VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.657468 DOI=10.3389/fgene.2021.657468 ISSN=1664-8021 ABSTRACT=

The availability of high-quality genome sequences of great ape species provides unprecedented opportunities for genomic analyses. Herein, we reviewed the recent progress in evolutionary comparative genomic studies of the existing great ape species, including human, chimpanzee, bonobo, gorilla, and orangutan. We elaborate discovery on evolutionary history, natural selection, structural variations, and new genes of these species, which is informative for understanding the origin of human-specific phenotypes.