AUTHOR=Kim Yongkang , Lee Sungyoung , Jang Jin-Young , Lee Seungyeoun , Park Taesung TITLE=Identifying miRNA-mRNA Integration Set Associated With Survival Time JOURNAL=Frontiers in Genetics VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.634922 DOI=10.3389/fgene.2021.634922 ISSN=1664-8021 ABSTRACT=
In the “personalized medicine” era, one of the most difficult problems is identification of combined markers from different omics platforms. Many methods have been developed to identify candidate markers for each type of omics data, but few methods facilitate the identification of multiple markers on multi-omics platforms. microRNAs (miRNAs) is well known to affect only indirectly phenotypes by regulating mRNA expression and/or protein translation. To take into account this knowledge into practice, we suggest a miRNA-mRNA integration model for survival time analysis, called