AUTHOR=Ma Chun-yu , Madden Pamela , Gontarz Paul , Wang Ting , Zhang Bo 

TITLE=FeatSNP: An Interactive Database for Brain-Specific Epigenetic Annotation of Human SNPs

JOURNAL=Frontiers in Genetics

VOLUME=10

YEAR=2019

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2019.00262

DOI=10.3389/fgene.2019.00262

ISSN=1664-8021

ABSTRACT=<p>FeatSNP is an online tool and a curated database for exploring 81 million common SNPs’ potential functional impact on the human brain. FeatSNP uses the brain transcriptomes of the human population to improve functional annotation of human SNPs by integrating transcription factor binding prediction, public eQTL information, and brain specific epigenetic landscape, as well as information of Topologically Associating Domains (TADs). FeatSNP supports both single and batched SNP searching, and its interactive user interface enables users to explore the functional annotations and generate publication-quality visualization results. FeatSNP is freely available on the internet at <ext-link ext-link-type="uri" xlink:href="http://FeatSNP.org" xmlns:xlink="http://www.w3.org/1999/xlink">FeatSNP.org</ext-link> with all major web browsers supported.</p>