AUTHOR=Zeisel Steven H. 

TITLE=A Conceptual Framework for Studying and Investing in Precision Nutrition

JOURNAL=Frontiers in Genetics

VOLUME=10

YEAR=2019

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2019.00200

DOI=10.3389/fgene.2019.00200

ISSN=1664-8021

ABSTRACT=<p>Nutrients and food-derived bioactive molecules must transit complex metabolic pathways, and these pathways vary between people. Metabolic heterogeneity is caused by genetic variation, epigenetic variation, differences in microbiome composition and function, lifestyle differences and by variation in environmental exposures. This review discusses a number of these sources of metabolic heterogeneity and presents some of the research investments that will be needed to make applications of precision nutrition practical.</p>