AUTHOR=Weldenegodguad Melak , Popov Ruslan , Pokharel Kisun , Ammosov Innokentyi , Ming Yao , Ivanova Zoya , Kantanen Juha TITLE=Whole-Genome Sequencing of Three Native Cattle Breeds Originating From the Northernmost Cattle Farming Regions JOURNAL=Frontiers in Genetics VOLUME=9 YEAR=2019 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2018.00728 DOI=10.3389/fgene.2018.00728 ISSN=1664-8021 ABSTRACT=
Northern Fennoscandia and the Sakha Republic in the Russian Federation represent the northernmost regions on Earth where cattle farming has been traditionally practiced. In this study, we performed whole-genome sequencing to genetically characterize three rare native breeds Eastern Finncattle, Western Finncattle and Yakutian cattle adapted to these northern Eurasian regions. We examined the demographic history, genetic diversity and unfolded loci under natural or artificial selection. On average, we achieved 13.01-fold genome coverage after mapping the sequencing reads on the bovine reference genome (UMD 3.1) and detected a total of 17.45 million single nucleotide polymorphisms (SNPs) and 1.95 million insertions-deletions (indels). We observed that the ancestral species (