AUTHOR=Ruden Douglas M. , Gurdziel Katherine , Aschner Michael TITLE=Frontiers in Toxicogenomics in the Twenty-First Century—the Grand Challenge: To Understand How the Genome and Epigenome Interact with the Toxic Environment at the Single-Cell, Whole-Organism, and Multi-Generational Level JOURNAL=Frontiers in Genetics VOLUME=8 YEAR=2017 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2017.00173 DOI=10.3389/fgene.2017.00173 ISSN=1664-8021