AUTHOR=Hernandez-Escalante Victor M. , Nava-Gonzalez Edna J. , Voruganti V. Saroja , Kent Jack W. , Haack Karin , Laviada-Molina Hugo A. , Molina-Segui Fernanda , Gallegos-Cabriales Esther C. , Lopez-Alvarenga Juan Carlos , Cole Shelley A. , Mezzles Marguerite J. , Comuzzie Anthony G. , Bastarrachea Raul A. TITLE=Replication of obesity and diabetes-related SNP associations in individuals from Yucatán, México JOURNAL=Frontiers in Genetics VOLUME=5 YEAR=2014 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2014.00380 DOI=10.3389/fgene.2014.00380 ISSN=1664-8021 ABSTRACT=
The prevalence of type 2 diabetes (T2D) is rising rapidly and in Mexicans is ~19%. T2D is affected by both environmental and genetic factors. Although specific genes have been implicated in T2D risk few of these findings are confirmed in studies of Mexican subjects. Our aim was to replicate associations of 39 single nucleotide polymorphisms (SNPs) from 10 genes with T2D-related phenotypes in a community-based Mexican cohort. Unrelated individuals (