AUTHOR=Saito Yoshimasa , Saito Hidetsugu TITLE=MicroRNAs in cancers and neurodegenerative disorders JOURNAL=Frontiers in Genetics VOLUME=3 YEAR=2012 URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2012.00194 DOI=10.3389/fgene.2012.00194 ISSN=1664-8021 ABSTRACT=
MicroRNAs (miRNAs) are small non-coding RNAs which function as endogenous silencers of various target genes. miRNAs are expressed in a tissue-specific manner and playing important roles in cell proliferation, apoptosis, and differentiation during mammalian development. Links between miRNAs and the initiation and progression of human diseases including cancer are becoming increasingly apparent. Recent studies have revealed that some miRNAs such as