Frontiers in Genetics

Original Research

Accepted on 05 Mar 2025

Identification of Mitochondrial Permeability Transition-related lncRNAs to develop a quantitative biomarker for prognosis and therapy of Breast Cancer

in RNA

Zhongshu Lin
Xinlu Wang
Guanxiang Hua
Fangmin Zhong
Wangxinjun Cheng
Yuxiang Qiu
Zhe Chi
Huan Zeng
Xiaozhong Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1510154

Original Research

Accepted on 05 Mar 2025

The Gene Signature Linked to Lactate Metabolism Predicts the Prognosis and Correlates with the Immune Status of Head and Neck Squamous Cell Carcinoma

in Cancer Genetics and Oncogenomics

Jian Xiao
Wei Li
Guolin Tan
Ru Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1540841

Original Research

Published on 05 Mar 2025

Multi-omics analysis reveals Jianpi formula-derived bioactive peptide-YG-22 potentially inhibited colorectal cancer via regulating epigenetic reprogram and signal pathway regulation

in Cancer Genetics and Oncogenomics

Jun Wang
Lijuan Zhu
Yuanyuan Li
Mingming Ding
Xiyu Wang
Bo Xiong
Hongyu Chen
Lisheng Chang
Wenli Chen
Bo Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1560172

141 views

Original Research

Published on 05 Mar 2025

Study on the mechanism of KIF18B affecting the malignant progression of glioblastoma cells

in Cancer Genetics and Oncogenomics

Xiangyue Su
Liji Huang
Wei Ma
Rong Wang
Xiangjian Zeng
Gangliang Wei
Suli Mai
Min Yang
Shifu Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1540342

142 views

Original Research

Published on 05 Mar 2025

Genetic discrimination in insurance and employment based on personalized risk stratification for breast cancer screening

in ELSI in Science and Genetics

Manuela Reveiz
Sarah Bouhouita-Guermech
Kristina M. Blackmore
Jocelyne Chiquette
Éric Demers
Michel Dorval
Laurence Lambert-Côté
Hermann Nabi
Nora Pashayan
Penny Soucy

Frontiers in Genetics

doi 10.3389/fgene.2025.1481863

290 views

Case Report

Published on 05 Mar 2025

A novel HMBS gene mutation in acute intermittent porphyria: a case report of abdominal pain, seizures, and reversible neuroimaging findings

in Neurogenomics

Wentao Dong
Bingliang Zeng
Xiaolian Wang
Rui Zhang
Pei Huang
Bing Fan
Min Yuan
Zicong Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1551832

101 views

Original Research

Published on 05 Mar 2025

Expression quantitative trait loci associated with performance traits, blood biochemical parameters, and cytokine profile in pigs

in Livestock Genomics

Felipe André Oliveira Freitas
Luiz F. Brito
Bárbara Silva-Vignato
Fernanda Nery Ciconello
Vivian Vezzoni de Almeida
Aline Silva Mello Cesar

Frontiers in Genetics

doi 10.3389/fgene.2025.1533424

218 views

Review

Published on 05 Mar 2025

Mechanism of action of lncRNA-NEAT1 in immune diseases

in RNA

Ruo-Xuan Zhang
Zi-Xuan Zhang
Xiang-Yu Zhao
Yi-Han Liu
Xiao-Meng Zhang
Qin Han
Xiao-Yu Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1501115

114 views

Brief Research Report

Published on 05 Mar 2025

Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis

in Genetics of Common and Rare Diseases

Elizabeth Gorman
Hongzheng Dai
Yanming Feng
William James Craigen
David C. Y. Chen
Fan Xia
Linyan Meng
Pengfei Liu
Robert Rigobello
Arpita Neogi

Frontiers in Genetics

doi 10.3389/fgene.2025.1488956

152 views

Review

Published on 05 Mar 2025

Sex differences in asthma: omics evidence and future directions

in Applied Genetic Epidemiology

Bichen Peng
Weiyi Ye
Shuai Liu
Yue Jiang
Ziang Meng
Miao Guo
Lili Zhi
Xiao Chang
Lei Shao

Frontiers in Genetics

doi 10.3389/fgene.2025.1560276

147 views

Brief Research Report

Published on 05 Mar 2025

Application of a novel RNA-protein interaction assay to develop inhibitors blocking RNA-binding of the HuR protein

in RNA

Larissa Filcenkova
Annika Reisbitzer
Benjamin Philipp Joseph
Verena Weber
Paolo Carloni
Giulia Rossetti
Sybille Krauß

Frontiers in Genetics

doi 10.3389/fgene.2025.1549304

130 views

Editorial

Published on 05 Mar 2025

Editorial: The role of genes and network pharmacology in new drug discovery

in Computational Genomics

Jingxin Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1578094

107 views

Case Report

Published on 05 Mar 2025

Lessons from a phenotypically normal infant with uniparental isodisomy of chromosome 21: a Case Report and review

in Molecular Cytogenetics

Yuying Zhu
Ke Wu
Cuicui Jiang
Qiumin Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544565

112 views

Original Research

Published on 05 Mar 2025

Differential responses of the intestine and liver transcriptome to high levels of plant proteins in diets for large yellow croaker (Larimichthys crocea)

in Livestock Genomics

Qiaozhen Ke
Yin Li
Huasong Weng
Baohua Chen
Jiaying Wang
Ji Zhao
Pengxin Jiang
Peng Xu
Tao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1540305

131 views

Original Research

Published on 05 Mar 2025

Identifying pathological myopia associated genes with GenePlexus in protein-protein interaction network

in Genetics of Common and Rare Diseases

Yuanyuan Luo
Yihan Wang
Lin Liu
Feiming Huang
Shiheng Lu
Yan Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1533567

122 views

Original Research

Published on 05 Mar 2025

Molecular diagnosis and preimplantation genetic testing for chromosome 1q21.1 recurrent microduplication

in Genetics of Common and Rare Diseases

Cuiting Peng
Han Chen
Fan Zhou
Hong Yang
Yutong Li
Yuezhi Keqie
Xu Zhao
He Wang
Ting Hu
Shanling Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1522406

143 views

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Articles

Identification of Mitochondrial Permeability Transition-related lncRNAs to develop a quantitative biomarker for prognosis and therapy of Breast Cancer

The Gene Signature Linked to Lactate Metabolism Predicts the Prognosis and Correlates with the Immune Status of Head and Neck Squamous Cell Carcinoma

Multi-omics analysis reveals Jianpi formula-derived bioactive peptide-YG-22 potentially inhibited colorectal cancer via regulating epigenetic reprogram and signal pathway regulation

Study on the mechanism of KIF18B affecting the malignant progression of glioblastoma cells

Genetic discrimination in insurance and employment based on personalized risk stratification for breast cancer screening

A novel HMBS gene mutation in acute intermittent porphyria: a case report of abdominal pain, seizures, and reversible neuroimaging findings

Expression quantitative trait loci associated with performance traits, blood biochemical parameters, and cytokine profile in pigs

Mechanism of action of lncRNA-NEAT1 in immune diseases

Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis

Sex differences in asthma: omics evidence and future directions

Application of a novel RNA-protein interaction assay to develop inhibitors blocking RNA-binding of the HuR protein

Editorial: The role of genes and network pharmacology in new drug discovery

Lessons from a phenotypically normal infant with uniparental isodisomy of chromosome 21: a Case Report and review

Differential responses of the intestine and liver transcriptome to high levels of plant proteins in diets for large yellow croaker (Larimichthys crocea)

Identifying pathological myopia associated genes with GenePlexus in protein-protein interaction network

Molecular diagnosis and preimplantation genetic testing for chromosome 1q21.1 recurrent microduplication