CASE REPORT article

Front. Gastroenterol.

Sec. Gastroenterology and Cancer

Volume 4 - 2025 | doi: 10.3389/fgstr.2025.1584899

Endometriosis presenting as a rectal stricture in a patient with ulcerative colitis and primary sclerosing cholangitis: A case report

Provisionally accepted
Daniel  ChorleyDaniel Chorley1,2*Ibrahim  MianIbrahim Mian2Deloshaan  SubhaharanDeloshaan Subhaharan2Pradeep  Kakkadasam RamaswamyPradeep Kakkadasam Ramaswamy2
  • 1Queensland Health, Brisbane, Australia
  • 2Gold Coast University Hospital, Southport, Queensland, Australia

The final, formatted version of the article will be published soon.

Patients with ulcerative colitis (UC) are at an increased risk of colorectal cancer (CRC), which is compounded in the presence of other risk factors such as primary sclerosing cholangitis (PSC) and stricture. We report a middle-aged lady who developed a rectal stricture on the background of ulcerative colitis and primary sclerosing cholangitis. Although initial endoscopic biopsies showed no dysplasia, the patient proceeded with a total colectomy due to the concern for an underlying malignancy. Histology of the rectal specimens revealed endometriosis at the site of the stricture. This case emphasises the importance of evaluating the risk factor profile for malignancy in patients with ulcerative colitis while also highlighting the need to consider alternative aetiologies for rectal strictures.

Keywords: Ulcerative colitis1, Endometrosis2, Stricture3, Primary Sclerosing Cholangitis4, Inflammatory bowel disease5, colorectal cancer6, Cancer surveillance7, Colectomy8

Received: 27 Feb 2025; Accepted: 22 Apr 2025.

Copyright: © 2025 Chorley, Mian, Subhaharan and Kakkadasam Ramaswamy. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Daniel Chorley, Queensland Health, Brisbane, Australia

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.