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CASE REPORT article
Front. Gastroenterol.
Sec. The Pancreas
Volume 4 - 2025 | doi: 10.3389/fgstr.2025.1554597
This article is part of the Research TopicNutrition in Pancreatic Diseases: The Role of Nutritional Status and Nutrition Therapy in the Management of Pancreatitis and Pancreatic CancerView all 4 articles
Groove Pancreatitis Accompanied by Duodenal Stenosis and Renal Insufficiency: A Case Report
Provisionally accepted- 1Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, China
- 2Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing city, China
- 3Nanjing Medical University, Nanjing, China
- 4Department Of General Surgery, Nanjing First Hospital, Nanjing city, China
- 5Department of Gastroenterology, Nanjing First Hospital, Nanjing Medical, Nanjing city, China
- 6Department of Radiology, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Liaoning Province, China
- 7Department of Gastroenterology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, 210006, Jiangsu, China., Nanjing city, China
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Groove pancreatitis (GP) is a rare form of chronic pancreatitis localized to the pancreaticoduodenal groove and is frequently associated with duodenal stenosis.We present a 45-year-old female with persistent nausea and vomiting, leading to dehydration, electrolyte imbalances, and renal insufficiency. Diagnostic imaging confirmed GP with duodenal stenosis. The renal insufficiency was primarily attributed to dehydration from severe vomiting, with hypokalemic metabolic alkalosis as a concomitant finding rather than the direct cause of kidney dysfunction.Early recognition of these systemic effects allowed prompt intervention with electrolyte correction, nutritional support, and pancreatic enzyme supplementation, which resulted in significant clinical improvement.This case highlights the importance of early diagnosis and management of groove pancreatitis, emphasizing the need to address its systemic complications, including renal insufficiency arising from complex fluid and electrolyte imbalances.
Keywords: Gr oove Pancr eatitis, Renal Insufficiency, Duodenal stenosis, Electr olyte Imbalance, Gastr ointestinal Obstr uction, Hypokalemic Alkalosis. Intr oduction
Received: 02 Jan 2025; Accepted: 18 Mar 2025.
Copyright: © 2025 Asnake, Wako, Qian, Zhu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jianguo Zhu, Department of Radiology, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Liaoning Province, China
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