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CASE REPORT article

Front. Gastroenterol.
Sec. Biliary and Pancreatic Research
Volume 3 - 2024 | doi: 10.3389/fgstr.2024.1425831

Initial presentation of pancreatic schwannoma as cystic pancreatic mass treated with classic Whipple's procedure

Provisionally accepted
Amanuel M. Woldeamanuel Amanuel M. Woldeamanuel 1Zekewos D. Jemaneh Zekewos D. Jemaneh 1*Nahom Zemedkun Nahom Zemedkun 1Serkalem Nurlegn Serkalem Nurlegn 1Henok Seife Henok Seife 2Yohannes Birhanu Yohannes Birhanu 2Bethelhem B. Belachew Bethelhem B. Belachew 3
  • 1 Lancet General Hospital, Addis Ababa, Ethiopia
  • 2 College of Health Sciences, Addis Ababa University, Addis Ababa, Addis Ababa, Ethiopia
  • 3 St. Paul's Hospital Millennium Medical College, Addis Ababa, Addis Ababa, Ethiopia

The final, formatted version of the article will be published soon.

    Pancreatic schwannomas are exceedingly rare tumors arising from Schwann cells of the peripheral nerve sheath within the pancreas. Often asymptomatic or presenting with nonspecific symptoms, these tumors pose a diagnostic challenge due to their mimicry of other pancreatic neoplasms on imaging studies. Histologically, pancreatic schwannomas demonstrate spindle cell proliferation with a distinct Immunohistochemical profile, including positive staining for S-100 protein. Surgical resection remains the cornerstone of treatment, with excellent long-term prognosis following complete excision. Here, we present a case report of a pancreatic schwannoma in a woman presenting with a cystic pancreatic mass, underscoring the importance of considering this rare entity in the differential diagnosis of pancreatic lesions.

    Keywords: Schwannoma, Pancreatic tumor, Pancreatic schwannoma, Cystic pancreatic mass, Whipple's procedure

    Received: 30 Apr 2024; Accepted: 07 Oct 2024.

    Copyright: © 2024 Woldeamanuel, Jemaneh, Zemedkun, Nurlegn, Seife, Birhanu and Belachew. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zekewos D. Jemaneh, Lancet General Hospital, Addis Ababa, Ethiopia

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