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CASE REPORT article
Front. Gastroenterol.
Sec. Gastroenterology and Cancer
Volume 3 - 2024 | doi: 10.3389/fgstr.2024.1386385
This article is part of the Research Topic Advances in GI and hepatic cancer mechanisms and therapeutic approaches View all 5 articles
Deep cystic gastritis: challenging the diagnosis
Provisionally accepted- 1 Affiliated Hospital of Hebei University of Engineering, Handan, Hebei Province, China
- 2 HanDan Central Hospital, Handan, China
- 3 Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, China
Deep cystic gastritis (GCP) is a cystic lesion formed by expansive growth of gastric glandular cells into the submucosal muscularis propria under the stimulation of inflammatory cells. Given its nonspecific presentation, it may represent a diagnostic challenge, especially in the differentiation of deep-involved cystic gastritis from highly differentiated adenocarcinoma. Therefore, histology and immunohistochemistry become crucial in the diagnosis of these cases. We report two cases of deep-seated cystic gastritis, both with gastric lesions detected on physical examination, with a focus on describing the pathohistologic as well as immunohistochemical features to provide a theoretical basis for GCP management.
Keywords: Deep cystic gastritis, Pathologic, diagnosis, Immunohistochemistry, gastric cancer
Received: 15 Feb 2024; Accepted: 21 Oct 2024.
Copyright: © 2024 Yuan, Tao, Li and guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
zhijuan guo, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, China
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