AUTHOR=Steube Arndt , Stallhofer Johannes , Stallmach Andreas TITLE=Fecal microbiota transfer to treat ulcerative colitis: Medical and legal challenges JOURNAL=Frontiers in Gastroenterology VOLUME=2 YEAR=2023 URL=https://www.frontiersin.org/journals/gastroenterology/articles/10.3389/fgstr.2023.1161610 DOI=10.3389/fgstr.2023.1161610 ISSN=2813-1169 ABSTRACT=
Ulcerative colitis (UC) is one of the main forms of chronic inflammatory bowel disease; however, despite intensive efforts, its etiology remains unclear. It is generally accepted that disturbances in the gastrointestinal microbiota (“dysbiosis”) contribute to the manifestation and perpetuation of UC. To date, treatment has focused on anti-inflammatory strategies; however, their widespread application is limited by side effects and primary/secondary loss of response. Following the resounding success of fecal microbiota transfer (FMT) to treat