AUTHOR=Liu Cenqin , Yuan Xin , Gao Hui , Zhang Zhixin , Wang Weihong , Xie Jiarong , Lu Hongpeng , Chen Jian , Yu Chaohui , Xu Lei TITLE=Real-word evaluation of differences in bowel preparation for colonoscopy between the digestive and the non-digestive physicians: A retrospective study JOURNAL=Frontiers in Gastroenterology VOLUME=Volume 1 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/gastroenterology/articles/10.3389/fgstr.2022.946459 DOI=10.3389/fgstr.2022.946459 ISSN=2813-1169 ABSTRACT=Abstract Introduction: Using real-world data, we compared the quality of bowel preparation instructed by the digestive and non-digestive physicians in outpatients for colonoscopy, and identified potential risk factors. Methods: This was a retrospective study based on real-world data, which was collected from the Ningbo First Hospital in China from December 2019 to October 2020. Outpatients included were classified into the digestive and the non-digestive physician groups according to the referring physician. The primary outcome was adequate bowel preparation measured by the Boston Bowel Preparation Scale (BBPS), namely, a BBPS score of 2 or higher in any colonic segment and a total score ≥ 6. Secondary outcomes included the total mean BBPS scores and possible risk factors associated with poor bowel preparation. Results: There were 671 outpatients included, with 392 in the digestive physician group and 279 in the non-digestive physician group. Adequate bowel preparation was 84.2% in the digestive physician group and 71.0% in the non-digestive physician group (odds ratio [OR] 1.50, p < 0.001), and the latter had lower total mean BBPS scores (6.12  1.33 vs 6.661.29, p < 0.001). The non-digestive physician was an independent risk factor according to the multivariate logistic regression analysis (OR 0.45, p < 0.001). Conclusion: The quality of bowel preparations instructed by non-digestive physicians was inferior to digestive physicians, which was a factor potentially associated with poor bowel preparation (ClinicalTrials.gov number: NCT04738578).