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ORIGINAL RESEARCH article
Front. Environ. Sci.
Sec. Toxicology, Pollution and the Environment
Volume 13 - 2025 | doi: 10.3389/fenvs.2025.1555341
Mapping Research Frontiers in Microplastics-Induced Oxidative Stress: A Bibliometric Analysis (2010-2024)
Provisionally accepted- School of Public Health, Kunming Medical University, Kunming, Yunnan Province, China
This study employs bibliometric analysis to uncover research trends and hotspots in oxidative stress induced by microplastics exposure from 2010 to 2024, providing a theoretical foundation for developing antioxidant intervention strategies. Analyzing 1,820 articles retrieved from the Web of Science Core Collection, methods such as Latent Dirichlet Allocation (LDA) modeling, keyword co-occurrence analysis, and temporal regression were applied to identify research themes, keyword associations, and evolving trends. The findings reveal significant growth in research activity, with health risk assessment and molecular mechanism studies emerging as primary focal areas. Oxidative stress was identified as a pivotal factor linking inflammation, gut microbiota dysbiosis, and apoptosis, with clustering analysis highlighting complex multisystem interactions. Temporal trends further emphasize a growing focus on health risk evaluation and antioxidant strategies. This study underscores the centrality of oxidative stress in microplastics toxicity, with dietary antioxidants like zinc and N-acetylcysteine showing promise in mitigating health risks. These insights provide valuable guidance for addressing microplastic-related health concerns and shaping future research directions.
Keywords: Microplastics exposure, Oxidative stress mechanisms, Health risk evaluation, Antioxidant strategies, environmental toxicology, bibliometric mapping 2.2.1 LDA Topic Modeling Analysis
Received: 04 Jan 2025; Accepted: 28 Mar 2025.
Copyright: © 2025 Xu, Yang, Chen, Gao and Jin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Fang Xu, School of Public Health, Kunming Medical University, Kunming, 650500, Yunnan Province, China
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