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Brief Research Report

Published on 27 Jan 2025

Activation of the Nrf2/HO-1 pathway restores N-acetylcysteine-induced impairment of the hypothalamus-pituitary-adrenal axis negative feedback by up-regulating GRα expression and down-regulating GRβ expression into pituitary glands

  • Amanda Silva Chaves
  • RaĂ­ssa Duarte Ventura
  • Maria Florencia Pacini
  • Nathalia Santos MagalhĂŁes
  • PatrĂ­cia Machado Rodrigues e Silva
  • Marco AurĂ©lio Martins
  • Ana Rosa PĂ©rez
  • Vinicius Frias Carvalho
Frontiers in Endocrinology
doi 10.3389/fendo.2025.1500630