Skip to main content

EDITORIAL article

Front. Endocrinol.

Sec. Bone Research

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1599232

This article is part of the Research Topic Sex-Related Differences In Bone Disease And Musculoskeletal Health View all 5 articles

Editorial: Sex-Related Differences In Bone Disease And Musculoskeletal Health

Provisionally accepted
  • 1 University of Bari Aldo Moro, Bari, Italy
  • 2 Bristol University, Anaheim, California, United States

The final, formatted version of the article will be published soon.

    computed tomography (QCT). The authors measured the age-and sex-related longitudinal changes in trabecular volumetric bone mineral density (vBMD) and vertebral body volume at the thoracolumbar spine in adults. The study included 168 adults. Thoracolumbar vBMD was higher in women compared with men before menopause, but were no longer evident after menopause, due to accelerated and more profound vBMD decline in women. Having excluded degenerative vertebrae, small increases were observed in vertebral body volume which were greater in males. In conclusion, sex-related differences in bone disease and musculoskeletal health are frequently observed and likely reflect a combination of nutritional, hormonal, behavioral and biomechanical factors.1. Chen P-J, Lu Y-C, Lu S-N, Liang F-W, Chuang H-Y. Association between osteoporosis and adiposity index reveals nonlinearity among postmenopausal women and linearity among men aged over 50 years. J Epidemiol Global Health. (2024) 14:1202-18. doi: 10.1007/s44197-024-00275-9

    Keywords: sex differece, sexual dimorfism, bone disease, muscoloskeletal health, Gender diff erences

    Received: 24 Mar 2025; Accepted: 01 Apr 2025.

    Copyright: © 2025 Brunetti and Tobias. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Giacomina Brunetti, University of Bari Aldo Moro, Bari, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    95% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more