REVIEW article
Front. Endocrinol.
Sec. Reproduction
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1577702
Non-Invasive Applications of Raman Spectroscopy in Assisted Reproduction
Provisionally accepted
- 1Department of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun, China
- 2School of Biology and Agricultural Engineering, Jilin University, Changchun, Hebei Province, China
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This review explores the non-invasive applications of Raman spectroscopy in assisted reproductive technology (ART). Raman spectroscopy, a powerful tool for analyzing biological samples, has shown great potential in enhancing ART outcomes through various applications such as sperm quality assessment, oocyte evaluation, and embryo selection. The non-destructive nature and high specificity of this technique enable detailed biochemical analysis at the cellular level, offering valuable insights into cellular processes without harming for the samples. The review highlights recent advancements and studies demonstrating the efficacy of Raman spectroscopy in improving the selection criteria for gametes and embryos, ultimately contributing to higher success rates in ART. Future perspectives on integrating Raman spectroscopy with other technologies to further enhance its applicability in reproductive medicine are also discussed.
Keywords: Raman spectroscopy, Assisted reproductive technology (ART), Gamete quality, Embryo viability, Non-invasive assessment
Received: 16 Feb 2025; Accepted: 14 Apr 2025.
Copyright: © 2025 Sui, Si, Chen, Lu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yingli Lu, Department of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun, China
Hongru Li, Department of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.