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ORIGINAL RESEARCH article
Front. Endocrinol.
Sec. Bone Research
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1558622
This article is part of the Research Topic Imaging-Based Methods for Fracture Risk Assessment View all 8 articles
Association between the minimal model of hip structure and risk of hip fracture in Chinese adults
Provisionally accepted- Changzhou No.2 People's Hospital, Changzhou, China
Background: Multiple studies have indicated that the minimal model of hip structure can enhance hip fracture risk assessment. This study aimed to investigate the independent association between minimal model variables and hip fracture risk in Han Chinese individuals.This cross-sectional study included 937 Han Chinese patients (248 with hip fractures). Minimal model variables were calculated from the hip structural analysis, including bone mineral density (BMD), femoral neck width (FNW), and Delta and Sigma values.Results: This study included 937 patients (293 men; mean age = 68.3 years). In logistic regression analyses, BMD increase (per 0.1 g/cm 2 ) correlated with a 45% reduction in the hip fracture risk (odds ratio [OR] = 0.55; 95% confidence interval [CI]: 0.45-0.68) after adjusting for all covariates. However, FNW (per 0.1 cm) and Sigma (per 0.01 cm) and Delta values (per 0.01 cm) were associated with increased risks (
Keywords: hip structure, Minimal model, delta, Sigma, Hip fracture
Received: 10 Jan 2025; Accepted: 28 Feb 2025.
Copyright: © 2025 Zhao, Bo, Bai, Zhao and Ye. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Dan Zhao, Changzhou No.2 People's Hospital, Changzhou, China
Xinhua Ye, Changzhou No.2 People's Hospital, Changzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.