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ORIGINAL RESEARCH article
Front. Endocrinol.
Sec. Reproduction
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1526056
This article is part of the Research Topic Male Reproduction and Oxidative Stress, Volume II View all 14 articles
Impact of dual residual risk of cholesterol and inflammation on adult male sex hormones: a cross-sectional study from nhanes
Provisionally accepted- 1 Sunshine Union Hospital, Weifang, China
- 2 Department of Anaesthesiology, Weifang People's Hospital, Weifang, Shandong Province, China
- 3 Department of Radiation Oncology, Weifang People's Hospital, Weifang, Shandong Province, China
Purpose: Sex hormones are closely linked to inflammation and lipid metabolism. This study explores the correlation of residual cholesterol risk and residual inflammation risk with sex hormones.Materials and Methods: Logistic regression and dose-response curve analyses were conducted to examine the associations of total testosterone (TT), Sex Hormone Binding Protein (SHBG), Estradiol (E2), and Free testosterone (FT) with low density lipoprotein cholesterol (LDL-C) and high sensitive c-reactive protein (hs-CRP). Testosterone deficiency, defined as TT below 300 ng/dL, was analyzed across various subgroups based on LDL-C and hs-CRP levels.
Keywords: Testosterone, Inflammation, Residual cholesterol, Residual Risk, Testosterone deficiency
Received: 11 Nov 2024; Accepted: 13 Feb 2025.
Copyright: © 2025 Zhou, Wang, Liu, Yu and Ju. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Guofeng Wang, Department of Anaesthesiology, Weifang People's Hospital, Weifang, Shandong Province, China
Li Liu, Department of Anaesthesiology, Weifang People's Hospital, Weifang, Shandong Province, China
Jie Yu, Sunshine Union Hospital, Weifang, China
Shiying Ju, Department of Radiation Oncology, Weifang People's Hospital, Weifang, 261000, Shandong Province, China
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