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ORIGINAL RESEARCH article

Front. Endocrinol.
Sec. Clinical Diabetes
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1479662

Correlation between Chinese visceral adiposity index and serum uric acid levels in type 2 diabetes mellitus patients

Provisionally accepted
Amina Swailla Araújo Intchasso Adotey Amina Swailla Araújo Intchasso Adotey Qian Zhang Qian Zhang mengxue chen mengxue chen Yang Jiao Yang Jiao Yin Zhang Yin Zhang Claudette Butoyi Claudette Butoyi Dong Wang Dong Wang Ling Yang Ling Yang Guoyue Yuan Guoyue Yuan JUE JIA JUE JIA *
  • Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    The Chinese Visceral Adiposity Index (CVAI), a measure of visceral adiposity dysfunction, is used to assess visceral fat (VFA) malfunction. This research was performed to evaluate the relationship between CVAI and serum uric acid levels in type 2 diabetes mellitus (T2DM) patients. Methods A total of 2268 patients with T2DM were enrolled in this study. We collected the general clinical information of patients, measured the basic anthropometric indicators, tested glycolipid metabolism and biochemical indicators, and measured the visceral and subcutaneous fat area with bioelectrical impedance technology. According to the quartiles of the CVAI, the T2DM patients were classified into four groups: group A (CVAI≤94.43), group B (94.43＜ CVAI≤118.75), group C (118.75＜CVAI≤143.95), and group D (CVAI≥143.95), each group has 567 participants. Participants were divided into hyperuricemia (HUA) and non-HUA groups, and the clinical data between the two groups was compared.Results Among quartiles of CVAI, as CVAI increased, the proportion of patients with HUA gradually increased. The correlation analysis showed that the majority of basal measures, glycolipid metabolism and biochemical indicators were positively correlated with CVAI. By comparison, the level of CVAI in the HUA group was significantly higher than non-HUA group.Meanwhile, through using the ROC curve, our study observed the more predictive value of CVAI than other obesity indicators for T2DM with HUA.Conclusion CVAI is a simple but effective indicator, which is significantly correlated with HUA in T2DM and can reflect the incidence of HUA in T2DM patients. As CVAI increased, the risk of HUA in T2DM patients increased. Therefore, we should pay more attention to the application of CVAI in T2DM.

    Keywords: type 2 diabetes mellitus, Obesity, Uric Acid, Chinese visceral adiposity index, Hyperuricemia

    Received: 12 Aug 2024; Accepted: 02 Jan 2025.

    Copyright: © 2025 Araújo Intchasso Adotey, Zhang, chen, Jiao, Zhang, Butoyi, Wang, Yang, Yuan and JIA. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: JUE JIA, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, China

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