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ORIGINAL RESEARCH article

Front. Endocrinol.

Sec. Clinical Diabetes

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1475822

Diabetes burden Attributable to Air Pollution from 1990~2021 and the Future Trends: a Population-based Study

Provisionally accepted
Qingsong Mao Qingsong Mao 1Xiaoyi Zhu Xiaoyi Zhu 2Xinyi Zhang Xinyi Zhang 3Yu-zhe Kong Yu-zhe Kong 2*
  • 1 Banan Hospital affiliated to Chongqing Medical University, Chongqing, China
  • 2 Xiangya School of Medicine, Central South University, Changsha, China
  • 3 College of Teacher Education, Wenzhou University, Wenzhou, Zhejiang Province, China

The final, formatted version of the article will be published soon.

    This investigation explores the worldwide impact of diabetes burden associated with air pollution, drawing on data from the Global Burden of Disease Study 2021.The influence of air pollution on diabetes burden was analyzed at global, regional, and national levels. The study considered variations across age groups and genders and explored the relationship between disease impact and the Socio-Demographic Index (SDI). Additionally, an ARIMA model was employed to predict the future incidence of diabetes burden related to air pollution until 2050.In 2021, approximately 281.91 thousand fatalities and 12.90 million disability-adjusted life years were attributed to diabetes burden due to air pollution, featuring an age-standardized mortality rate (ASMR) of 3.3234 (95% UI, 1.9549-4.6634) and an age-standardized DALY rate (ASDR) of 148.9167 (95% UI, 86.5013-224.9116) per 100,000 individuals.. There was a noticeable escalation in the disease burden over the period studied.The most severe effects were noted in individuals aged 60 and above. The data also revealed a higher disease burden among males. Forecasting suggests that while low SDI regions might see a decrease in death rates, lower-middle SDI areas could face an increase in standardized mortality rates. On a national scale, Russia, Mexico, and several African nations are predicted to experience rising diabetes burden attributable to air pollution mortality rates and age-standardized mortality rates from now to 2050.South Asia and Africa are anticipated to witness substantial growth in agestandardized death rates compared to other areas.The results provide essential insights for developing preventive strategies for diabetes burden and measures to mitigate air pollution.

    Keywords: diabetes, Air Pollution, Mortality forecasting, Epidemiology, disease burden

    Received: 04 Aug 2024; Accepted: 07 Mar 2025.

    Copyright: © 2025 Mao, Zhu, Zhang and Kong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Yu-zhe Kong, Xiangya School of Medicine, Central South University, Changsha, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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